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  1. Hyaluronic acid (HA) is widely distributed in human connective tissue, and its unique biological and physicochemical properties and ability to facilitate biological structure repair make it a promising candida...

    Authors: Han Chen, Huaqian Xue, Huanxuan Zeng, Minghai Dai, Chengxuan Tang and Liangle Liu
    Citation: Biomaterials Research 2023 27:137
  2. The emergence of cancer immunotherapies, notably immune checkpoint inhibitors, has revolutionized anti-cancer treatments. These treatments, however, have been reported to be effective in a limited range of can...

    Authors: Jaehyun Kim, Minjeong Kim, Seok-Beom Yong, Heesoo Han, Seyoung Kang, Shayan Fakhraei Lahiji, Sangjin Kim, Juhyeong Hong, Yuha Seo and Yong-Hee Kim
    Citation: Biomaterials Research 2023 27:136
  3. Noninvasive monitoring of tear glucose levels can be convenient for patients to manage their diabetes mellitus. However, there are issues with monitoring tear glucose levels, such as the invasiveness of some m...

    Authors: Sijin Park, Dong Yeon Nam, Hee-Jae Jeon, Jae Hoon Han, Dawon Jang, Juil Hwang, Yeong-Seo Park, Young-Geun Han, Young Bin Choy and Dong Yun Lee
    Citation: Biomaterials Research 2023 27:135
  4. Tumor-derived exosomes are critical elements of the cell–cell communication response to various stimuli. This study aims to reveal that the histone deacetylase 5 (HDAC5) and p53 interaction upon radiation in h...

    Authors: Seung Min Lee, Jeongin Cho, Sujin Choi, Dong Ha Kim, Je-Won Ryu, Inki Kim, Dong-Cheol Woo, Young Hoon Sung, Jin-Yong Jeong, In-Jeoung Baek, Chan-Gi Pack, Jin Kyung Rho, Sang-wook Lee and Chang Hoon Ha
    Citation: Biomaterials Research 2023 27:134
  5. Drug nanocarriers can markedly reduce the toxicities and side effects of encapsulated chemotherapeutic drugs in the clinic. However, these drug nanocarriers have little effect on eradicating breast cancer stem...

    Authors: Li Lv, Yonghui Shi, Zhicheng Deng, Jiajia Xu, Zicong Ye, Jianxiong He, Guanghui Chen, Xiaoxia Yu, Junyan Wu, Xingzhen Huang and Guocheng Li
    Citation: Biomaterials Research 2023 27:133
  6. Bone tissue regeneration is regulated by complex events, including inflammation, osteoinduction, and remodeling. Therefore, to induce the complete restoration of defective bone tissue, biomaterials with the ab...

    Authors: Hayeon Byun, Gyu Nam Jang, Hyewoo Jeong, Jinkyu Lee, Seung Jae Huh, Sangmin Lee, Eunhyung Kim and Heungsoo Shin
    Citation: Biomaterials Research 2023 27:132
  7. EAU is an inflammatory disease usually characterized by autoinflammation and autoimmunity and is aggravated by excessive generation of ROS. Conventional hormone therapy often has more adverse effects. It is ur...

    Authors: Zhengxuan Jiang, Kun Liang, Xiang Gao, Fan Cao, Guangqi An, Siyu Gui, Weiwei Tang, Liping Du, Liming Tao and Xianwen Wang
    Citation: Biomaterials Research 2023 27:131
  8. Extracellular vesicles (EVs) are nanosized particles that are released from cells and reflect the characteristics of the mother cell. Recently, the EVs have been used in several types of studies across many di...

    Authors: Won-Kyu Rhim, Jun Yong Kim, Seung Yeon Lee, Seung-Gyu Cha, Jeong Min Park, Hyeon Jeong Park, Chun Gwon Park and Dong Keun Han
    Citation: Biomaterials Research 2023 27:130
  9. The regulation of dose-dependent biological effects induced by biodegradation is a challenge for the production of biodegradable bone-substitute materials, especially biodegradable zinc (Zn) -based materials. ...

    Authors: Meijing Liu, Junlong Tan, Shuang Li, Chaoyang Sun, Xiangning Liu, Hongtao Yang and Xiaogang Wang
    Citation: Biomaterials Research 2023 27:129
  10. Molecular self-assembly has received considerable attention in biomedical fields as a simple and effective method for developing biomolecular nanostructures. Self-assembled nanostructures can exhibit high bind...

    Authors: Ji-eun Kim, Jeon Hyeong Kang, Woo Hyun Kwon, Inseo Lee, Sang Jun Park, Chun-Ho Kim, Woo-jin Jeong, Jun Shik Choi and Kyobum Kim
    Citation: Biomaterials Research 2023 27:127
  11. To overcome the limitations of current alternative therapies for chronic kidney disease (CKD), tissue engineering-mediated regeneration strategies have demonstrated the possibilities for complete kidney tissue...

    Authors: Seung-Gyu Cha, Won-Kyu Rhim, Jun Yong Kim, Eun Hye Lee, Seung Yeon Lee, Jeong Min Park, Jeoung Eun Lee, Hyeji Yoon, Chun Gwon Park, Bum Soo Kim, Tae Gyun Kwon, Youngmi Lee, Dong Ryul Lee and Dong Keun Han
    Citation: Biomaterials Research 2023 27:126
  12. To realize imaging-guided multi-modality cancer therapy with minimal side effects remains highly challenging.

    Authors: Xiaozhe Wang, Xiaofeng Ren, Jie Yang, Zican Zhao, Xiaoyu Zhang, Fan Yang, Zheye Zhang, Peng Chen, Liping Li and Ruiping Zhang
    Citation: Biomaterials Research 2023 27:125
  13. Recently, increased attention has been given on exosomes as ideal nanocarriers of drugs owing to their intrinsic properties that facilitate the transport of biomolecular cargos. However, large-scale exosome pr...

    Authors: Hochung Jang, Hyosuk Kim, Eun Hye Kim, Geonhee Han, Yeongji Jang, Yelee Kim, Jong Won Lee, Sang Chul Shin, Eunice EunKyeong Kim, Sun Hwa Kim and Yoosoo Yang
    Citation: Biomaterials Research 2023 27:124
  14. Musculoskeletal disorders (MSDs), which include a range of pathologies affecting bones, cartilage, muscles, tendons, and ligaments, account for a significant portion of the global burden of disease. While phar...

    Authors: Zhenhe Zhang, Rong Wang, Hang Xue, Samuel Knoedler, Yongtao Geng, Yuheng Liao, Michael Alfertshofer, Adriana C. Panayi, Jie Ming, Bobin Mi and Guohui Liu
    Citation: Biomaterials Research 2023 27:123
  15. Mesenchymal stem cells (MSCs) have gained significant attention for diverse biomedical applications, including cell-based therapy. Hence, in vitro expansion of MSCs is critical; however, in vitro MSC culture, ...

    Authors: Chiseon Ryu, Minseo Lee and Jae Young Lee
    Citation: Biomaterials Research 2023 27:122
  16. Triple-negative breast cancer (TNBC) is an aggressive, metastatic and apparently drug-resistant subtype of breast cancer with a higher immune response compared to other types of breast cancer. Photodynamic the...

    Authors: Xiaoyan Liang, Min Mu, Bo Chen, Rangrang Fan, Haifeng Chen, Bingwen Zou, Bo Han and Gang Guo
    Citation: Biomaterials Research 2023 27:120
  17. Non-intrusive imaging of gastrointestinal (GI) tract using computed tomography (CT) contrast agents is of the most significant issues in the diagnosis and treatment of GI diseases. Moreover, spectral CT, which...

    Authors: Xiaoling Che, Chunmei Yang, Liping Pan, Didi Gu, Guidong Dai, Jian Shu and Lu Yang
    Citation: Biomaterials Research 2023 27:119
  18. Melanoma is a highly aggressive form of skin cancer with increasing incidence and mortality rates. Chemotherapy, the primary treatment for melanoma, is limited by hypoxia-induced drug resistance and suppressed...

    Authors: Han Zhang, Liangshan Hu, Wei Xiao, Yanqiong Su and Donglin Cao
    Citation: Biomaterials Research 2023 27:118
  19. There is a great clinical need and it remains a challenge to develop artificial soft tissue constructs that can mimic the biomechanical properties and bioactivity of natural tissue. This is partly due to the l...

    Authors: Karl Heinrich Schneider, Benjamin J. Goldberg, Onur Hasturk, Xuan Mu, Marvin Dötzlhofer, Gabriela Eder, Sophia Theodossiou, Luis Pichelkastner, Peter Riess, Sabrina Rohringer, Herbert Kiss, Andreas H. Teuschl-Woller, Vincent Fitzpatrick, Marjan Enayati, Bruno K. Podesser, Helga Bergmeister…
    Citation: Biomaterials Research 2023 27:117
  20. Malignant bone tumors are characterized by severe disability rate, mortality rate, and heavy recurrence rate owing to the complex pathogenesis and insidious disease progression, which seriously affect the term...

    Authors: Bo Chao, Jianhang Jiao, Lili Yang, Yang Wang, Weibo Jiang, Tong Yu, Linfeng Wang, He Liu, Han Zhang, Zhonghan Wang and Minfei Wu
    Citation: Biomaterials Research 2023 27:116
  21. Coatings of metal–organic frameworks (MOFs) have potential applications in surface modification for medical implants, tissue engineering, and drug delivery systems. Therefore, developing an applicable method f...

    Authors: Mohammad Mehdi Sabzehmeidani and Mahmood Kazemzad
    Citation: Biomaterials Research 2023 27:115
  22. Cancer is a complex illness that presents significant challenges in its understanding and treatment. The classic definition, "a group of diseases characterized by the uncontrolled growth and spread of abnormal...

    Authors: Nimeet Desai, Pratik Katare, Vaishali Makwana, Sagar Salave, Lalitkumar K. Vora and Jyotsnendu Giri
    Citation: Biomaterials Research 2023 27:113
  23. Colorectal cancer (CRC) is a prominent global cancer with high mortality rates among human beings. Efficient diagnosis and treatment have always been a challenge for CRC management. Fluorescence guided cancer ...

    Authors: Runsha Xiao, Fan Zheng, Kuo Kang, Lei Xiao, Anyao Bi, Yiting Chen, Qi Zhou, Xueping Feng, Zhikang Chen, Hao Yin, Wei Wang, Zihua Chen, Xiaomiao Cheng and Wenbin Zeng
    Citation: Biomaterials Research 2023 27:112
  24. Acute myeloid leukemia (AML) is a hematological malignancy that remains a therapeutic challenge due to the high incidence of disease relapse. To better understand resistance mechanisms and identify novel thera...

    Authors: Dana M. Alhattab, Ioannis Isaioglou, Salwa Alshehri, Zainab N. Khan, Hepi H. Susapto, Yanyan Li, Yara Marghani, Arwa A. Alghuneim, Rubén Díaz-Rúa, Sherin Abdelrahman, Shuroug AL-Bihani, Farid Ahmed, Raed I. Felimban, Heba Alkhatabi, Raed Alserihi, Malak Abedalthagafi…
    Citation: Biomaterials Research 2023 27:111
  25. Transarterial radioembolization (TARE) with 90Y-labeled glass and resin microspheres is one of the primary treatment strategies for advanced-stage primary and metastatic hepatocellular carcinoma (HCC). However, d...

    Authors: Liu Xiao, Yuhao Li, Ruiman Geng, Lihong Chen, Peng Yang, Mingyu Li, Xia Luo, Yuchuan Yang, Lin Li and Huawei Cai
    Citation: Biomaterials Research 2023 27:110
  26. Stroke is the second leading cause of mortality and disability worldwide. Poststroke rehabilitation is still unsatisfactory in clinics, which brings great pain and economic burdens to stroke patients. In this ...

    Authors: Zongjian Liu, Shulei Zhang, Yuanyuan Ran, Huimin Geng, Fuhai Gao, Guiqin Tian, Zengguo Feng, Jianing Xi, Lin Ye and Wei Su
    Citation: Biomaterials Research 2023 27:108
  27. The secretomes of mesenchymal stem cells (MSCs) have great therapeutic potential and thereby their efficient delivery into the target site is of particular interest. Here, we propose a new strategy of hMSCs-de...

    Authors: Jae Won Kwon, Cininta Savitri, Byoungha An, Seung Won Yang and Kwideok Park
    Citation: Biomaterials Research 2023 27:107
  28. Authors: Gun Hee Cho, Hyun Cheol Bae, Won Young Cho, Eui Man Jeong, Hee Jung Park, Ha Ru Yang, Sun Young Wang, You Jung Kim, Dong Myung Shin, Hyung Min Chung, In Gyu Kim and Hyuk-Soo Han
    Citation: Biomaterials Research 2023 27:106

    The original article was published in Biomaterials Research 2023 27:54

  29. Hypoxia is a frequent characteristic observed in solid tumors and is strongly associated with tumor metastasis, angiogenesis, and drug resistance. While the vasculature of hypoxic tumor tissues poses obstacles...

    Authors: Jie Dai, Jianmei Li, Yuqin Zhang, Qian Wen, Yun Lu, Yu Fan, Fancai Zeng, Zhiyong Qian, Yan Zhang and Shaozhi Fu
    Citation: Biomaterials Research 2023 27:105
  30. Long-term drug evaluation heavily relies upon rodent models. Drug discovery methods to reduce animal models in oncology may include three-dimensional (3D) cellular systems that take into account tumor microenv...

    Authors: Elly De Vlieghere, Koen Van de Vijver, Eva Blondeel, Nathan Carpentier, Rouba Ghobeira, Jarne Pauwels, Sebastian Riemann, Manon Minsart, Charlotte Fieuws, Johanna Mestach, Ans Baeyens, Nathalie De Geyter, Charlotte Debbaut, Hannelore Denys, Benedicte Descamps, Kathleen Claes…
    Citation: Biomaterials Research 2023 27:104
  31. Fibrosis plays an important role in both normal physiological and pathological phenomena as fibroblasts differentiate to myofibroblasts. The activation of fibroblasts is determined through interactions with th...

    Authors: Nhuan T. Do, Sun Young Lee, Yoon Seo Lee, ChaeHo Shin, Daeho Kim, Tae Geol Lee, Jin Gyeong Son and Se-Hwa Kim
    Citation: Biomaterials Research 2023 27:103
  32. Nano-sized drug delivery system has been widely studied as a potential technique to promote tumor-specific delivery of anticancer drugs due to its passive targeting property, but resulting in very restricted i...

    Authors: Jeongrae Kim, Sunejeong Song, Minjun Gwak, Hanhee Cho, Wan Su Yun, Namcheol Hwang, Jinseong Kim, Jun Seo Lee, Dong-Hwee Kim, Hyuncheol Kim, Seong Ik Jeon, Tae-il Kim and Kwangmeyung Kim
    Citation: Biomaterials Research 2023 27:102
  33. Neural stem cells (NSCs) derived from the embryonic spinal cord are excellent candidates for the cellular regeneration of lost neural cells after spinal cord injury (SCI). Semaphorin 3 A (Sema3A) is well known...

    Authors: Seong Jun Kim, Wan-Kyu Ko, Gong Ho Han, Daye Lee, Min Jai Cho, Seung Hun Sheen and Seil Sohn
    Citation: Biomaterials Research 2023 27:101
  34. Endometriosis is a common gynecological disease in women of childbearing age. Commonly used treatment methods, such as endocrine and surgical therapies, display poor therapeutic effects with a high relapse pro...

    Authors: Wei Tian, Chenyu Wang, Ran Chu, Haiyan Ge, Xiao Sun and Mingjiang Li
    Citation: Biomaterials Research 2023 27:100
  35. In recent years, cardiovascular disease in particular myocardial infarction (MI) has become the predominant cause of human disability and mortality in the clinical setting. The restricted capacity of adult car...

    Authors: Hassan Amini, Atieh Rezaei Namjoo, Maryam Taghavi Narmi, Narges Mardi, Samaneh Narimani, Ozra Naturi, Nafiseh Didar Khosrowshahi, Reza Rahbarghazi, Solmaz Saghebasl, Shahriar Hashemzadeh and Mohammad Nouri
    Citation: Biomaterials Research 2023 27:99
  36. Alzheimer’s disease is a neurodegenerative disorder, and Aβ aggregation is considered to be the central process implicated in its pathogenesis. Current treatments are faced by challenges such as serious side e...

    Authors: Yi-Wen Lin, Chih-Hsiang Fang, Ya-Jyun Liang, Ching-Yun Yang, Wei-Ting Kuo and Feng-Huei Lin
    Citation: Biomaterials Research 2023 27:98
  37. For some ICU patients, an artificial airway must be established with an endotracheal tube, but Candida albicans can easily adhere to the tube surface and form a biofilm, leading to potentially life threatening fu...

    Authors: Yunyun Wei, Jianfeng Qiu, Ziqiang Han, Xuanyi Wang, Hui Zhang, Xinya Hou, Xiangwei Lv and Xiaolong Mao
    Citation: Biomaterials Research 2023 27:97
  38. Biofilm formation on medical device surfaces is a persistent problem that shelters bacteria and encourages infections and implant rejection. One promising approach to tackle this problem is to coat the medical...

    Authors: Cecil Cherian Lukose, Ioannis Anestopoulos, Iraklis-Stavros Panagiotidis, Guillaume Zoppi, Anna M. Black, Lynn G. Dover, Leon Bowen, Ángel Serrano-Aroca, Terence Xiaoteng Liu, Lorenzo Mendola, Davide Morrone, Mihalis I. Panayiotidis and Martin Birkett
    Citation: Biomaterials Research 2023 27:93
  39. Colorectal cancer (CRC) is the second most deadly cancer worldwide, with chemo-resistance remaining a major obstacle in CRC treatment. Notably, the imbalance of redox homeostasis-mediated ferroptosis and the m...

    Authors: Hao Jiang, Hailong Tian, Zhihan Wang, Bowen Li, Rui Chen, Kangjia Luo, Shuaijun Lu, Edouard C. Nice, Wei Zhang, Canhua Huang, Yuping Zhou, Shaojiang Zheng and Feng Gao
    Citation: Biomaterials Research 2023 27:92
  40. Glioblastoma is a highly malignant brain tumor associated with poor prognosis. Conventional therapeutic approaches have limitations due to their toxic effects on normal tissue and the development of tumor cell...

    Authors: Hyung Shik Kim, Jae Hak Seol, Hae Hyun Hwang and Dong Yun Lee
    Citation: Biomaterials Research 2023 27:89
  41. Drug-resistant bacterial infections in chronic wounds are a persistent issue, as they are resistant to antibiotics and can cause excessive inflammation due to generation of reactive oxygen species (ROS). An ef...

    Authors: Jiahui Zhao, Tengfei Xu, Jichao Sun, Haitao Yuan, Mengyun Hou, Zhijie Li, Jigang Wang and Zhen Liang
    Citation: Biomaterials Research 2023 27:88