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  1. Musculoskeletal disorders (MSDs), which include a range of pathologies affecting bones, cartilage, muscles, tendons, and ligaments, account for a significant portion of the global burden of disease. While phar...

    Authors: Zhenhe Zhang, Rong Wang, Hang Xue, Samuel Knoedler, Yongtao Geng, Yuheng Liao, Michael Alfertshofer, Adriana C. Panayi, Jie Ming, Bobin Mi and Guohui Liu
    Citation: Biomaterials Research 2023 27:123
  2. Mesenchymal stem cells (MSCs) have gained significant attention for diverse biomedical applications, including cell-based therapy. Hence, in vitro expansion of MSCs is critical; however, in vitro MSC culture, ...

    Authors: Chiseon Ryu, Minseo Lee and Jae Young Lee
    Citation: Biomaterials Research 2023 27:122
  3. Triple-negative breast cancer (TNBC) is an aggressive, metastatic and apparently drug-resistant subtype of breast cancer with a higher immune response compared to other types of breast cancer. Photodynamic the...

    Authors: Xiaoyan Liang, Min Mu, Bo Chen, Rangrang Fan, Haifeng Chen, Bingwen Zou, Bo Han and Gang Guo
    Citation: Biomaterials Research 2023 27:120
  4. Non-intrusive imaging of gastrointestinal (GI) tract using computed tomography (CT) contrast agents is of the most significant issues in the diagnosis and treatment of GI diseases. Moreover, spectral CT, which...

    Authors: Xiaoling Che, Chunmei Yang, Liping Pan, Didi Gu, Guidong Dai, Jian Shu and Lu Yang
    Citation: Biomaterials Research 2023 27:119
  5. Melanoma is a highly aggressive form of skin cancer with increasing incidence and mortality rates. Chemotherapy, the primary treatment for melanoma, is limited by hypoxia-induced drug resistance and suppressed...

    Authors: Han Zhang, Liangshan Hu, Wei Xiao, Yanqiong Su and Donglin Cao
    Citation: Biomaterials Research 2023 27:118
  6. There is a great clinical need and it remains a challenge to develop artificial soft tissue constructs that can mimic the biomechanical properties and bioactivity of natural tissue. This is partly due to the l...

    Authors: Karl Heinrich Schneider, Benjamin J. Goldberg, Onur Hasturk, Xuan Mu, Marvin Dötzlhofer, Gabriela Eder, Sophia Theodossiou, Luis Pichelkastner, Peter Riess, Sabrina Rohringer, Herbert Kiss, Andreas H. Teuschl-Woller, Vincent Fitzpatrick, Marjan Enayati, Bruno K. Podesser, Helga Bergmeister…
    Citation: Biomaterials Research 2023 27:117
  7. Malignant bone tumors are characterized by severe disability rate, mortality rate, and heavy recurrence rate owing to the complex pathogenesis and insidious disease progression, which seriously affect the term...

    Authors: Bo Chao, Jianhang Jiao, Lili Yang, Yang Wang, Weibo Jiang, Tong Yu, Linfeng Wang, He Liu, Han Zhang, Zhonghan Wang and Minfei Wu
    Citation: Biomaterials Research 2023 27:116
  8. Coatings of metal–organic frameworks (MOFs) have potential applications in surface modification for medical implants, tissue engineering, and drug delivery systems. Therefore, developing an applicable method f...

    Authors: Mohammad Mehdi Sabzehmeidani and Mahmood Kazemzad
    Citation: Biomaterials Research 2023 27:115
  9. Cancer is a complex illness that presents significant challenges in its understanding and treatment. The classic definition, "a group of diseases characterized by the uncontrolled growth and spread of abnormal...

    Authors: Nimeet Desai, Pratik Katare, Vaishali Makwana, Sagar Salave, Lalitkumar K. Vora and Jyotsnendu Giri
    Citation: Biomaterials Research 2023 27:113
  10. Colorectal cancer (CRC) is a prominent global cancer with high mortality rates among human beings. Efficient diagnosis and treatment have always been a challenge for CRC management. Fluorescence guided cancer ...

    Authors: Runsha Xiao, Fan Zheng, Kuo Kang, Lei Xiao, Anyao Bi, Yiting Chen, Qi Zhou, Xueping Feng, Zhikang Chen, Hao Yin, Wei Wang, Zihua Chen, Xiaomiao Cheng and Wenbin Zeng
    Citation: Biomaterials Research 2023 27:112
  11. Acute myeloid leukemia (AML) is a hematological malignancy that remains a therapeutic challenge due to the high incidence of disease relapse. To better understand resistance mechanisms and identify novel thera...

    Authors: Dana M. Alhattab, Ioannis Isaioglou, Salwa Alshehri, Zainab N. Khan, Hepi H. Susapto, Yanyan Li, Yara Marghani, Arwa A. Alghuneim, Rubén Díaz-Rúa, Sherin Abdelrahman, Shuroug AL-Bihani, Farid Ahmed, Raed I. Felimban, Heba Alkhatabi, Raed Alserihi, Malak Abedalthagafi…
    Citation: Biomaterials Research 2023 27:111
  12. Transarterial radioembolization (TARE) with 90Y-labeled glass and resin microspheres is one of the primary treatment strategies for advanced-stage primary and metastatic hepatocellular carcinoma (HCC). However, d...

    Authors: Liu Xiao, Yuhao Li, Ruiman Geng, Lihong Chen, Peng Yang, Mingyu Li, Xia Luo, Yuchuan Yang, Lin Li and Huawei Cai
    Citation: Biomaterials Research 2023 27:110
  13. Stroke is the second leading cause of mortality and disability worldwide. Poststroke rehabilitation is still unsatisfactory in clinics, which brings great pain and economic burdens to stroke patients. In this ...

    Authors: Zongjian Liu, Shulei Zhang, Yuanyuan Ran, Huimin Geng, Fuhai Gao, Guiqin Tian, Zengguo Feng, Jianing Xi, Lin Ye and Wei Su
    Citation: Biomaterials Research 2023 27:108
  14. The secretomes of mesenchymal stem cells (MSCs) have great therapeutic potential and thereby their efficient delivery into the target site is of particular interest. Here, we propose a new strategy of hMSCs-de...

    Authors: Jae Won Kwon, Cininta Savitri, Byoungha An, Seung Won Yang and Kwideok Park
    Citation: Biomaterials Research 2023 27:107
  15. Authors: Gun Hee Cho, Hyun Cheol Bae, Won Young Cho, Eui Man Jeong, Hee Jung Park, Ha Ru Yang, Sun Young Wang, You Jung Kim, Dong Myung Shin, Hyung Min Chung, In Gyu Kim and Hyuk-Soo Han
    Citation: Biomaterials Research 2023 27:106

    The original article was published in Biomaterials Research 2023 27:54

  16. Hypoxia is a frequent characteristic observed in solid tumors and is strongly associated with tumor metastasis, angiogenesis, and drug resistance. While the vasculature of hypoxic tumor tissues poses obstacles...

    Authors: Jie Dai, Jianmei Li, Yuqin Zhang, Qian Wen, Yun Lu, Yu Fan, Fancai Zeng, Zhiyong Qian, Yan Zhang and Shaozhi Fu
    Citation: Biomaterials Research 2023 27:105
  17. Long-term drug evaluation heavily relies upon rodent models. Drug discovery methods to reduce animal models in oncology may include three-dimensional (3D) cellular systems that take into account tumor microenv...

    Authors: Elly De Vlieghere, Koen Van de Vijver, Eva Blondeel, Nathan Carpentier, Rouba Ghobeira, Jarne Pauwels, Sebastian Riemann, Manon Minsart, Charlotte Fieuws, Johanna Mestach, Ans Baeyens, Nathalie De Geyter, Charlotte Debbaut, Hannelore Denys, Benedicte Descamps, Kathleen Claes…
    Citation: Biomaterials Research 2023 27:104
  18. Fibrosis plays an important role in both normal physiological and pathological phenomena as fibroblasts differentiate to myofibroblasts. The activation of fibroblasts is determined through interactions with th...

    Authors: Nhuan T. Do, Sun Young Lee, Yoon Seo Lee, ChaeHo Shin, Daeho Kim, Tae Geol Lee, Jin Gyeong Son and Se-Hwa Kim
    Citation: Biomaterials Research 2023 27:103
  19. Nano-sized drug delivery system has been widely studied as a potential technique to promote tumor-specific delivery of anticancer drugs due to its passive targeting property, but resulting in very restricted i...

    Authors: Jeongrae Kim, Sunejeong Song, Minjun Gwak, Hanhee Cho, Wan Su Yun, Namcheol Hwang, Jinseong Kim, Jun Seo Lee, Dong-Hwee Kim, Hyuncheol Kim, Seong Ik Jeon, Tae-il Kim and Kwangmeyung Kim
    Citation: Biomaterials Research 2023 27:102
  20. Neural stem cells (NSCs) derived from the embryonic spinal cord are excellent candidates for the cellular regeneration of lost neural cells after spinal cord injury (SCI). Semaphorin 3 A (Sema3A) is well known...

    Authors: Seong Jun Kim, Wan-Kyu Ko, Gong Ho Han, Daye Lee, Min Jai Cho, Seung Hun Sheen and Seil Sohn
    Citation: Biomaterials Research 2023 27:101
  21. Endometriosis is a common gynecological disease in women of childbearing age. Commonly used treatment methods, such as endocrine and surgical therapies, display poor therapeutic effects with a high relapse pro...

    Authors: Wei Tian, Chenyu Wang, Ran Chu, Haiyan Ge, Xiao Sun and Mingjiang Li
    Citation: Biomaterials Research 2023 27:100
  22. In recent years, cardiovascular disease in particular myocardial infarction (MI) has become the predominant cause of human disability and mortality in the clinical setting. The restricted capacity of adult car...

    Authors: Hassan Amini, Atieh Rezaei Namjoo, Maryam Taghavi Narmi, Narges Mardi, Samaneh Narimani, Ozra Naturi, Nafiseh Didar Khosrowshahi, Reza Rahbarghazi, Solmaz Saghebasl, Shahriar Hashemzadeh and Mohammad Nouri
    Citation: Biomaterials Research 2023 27:99
  23. Alzheimer’s disease is a neurodegenerative disorder, and Aβ aggregation is considered to be the central process implicated in its pathogenesis. Current treatments are faced by challenges such as serious side e...

    Authors: Yi-Wen Lin, Chih-Hsiang Fang, Ya-Jyun Liang, Ching-Yun Yang, Wei-Ting Kuo and Feng-Huei Lin
    Citation: Biomaterials Research 2023 27:98
  24. For some ICU patients, an artificial airway must be established with an endotracheal tube, but Candida albicans can easily adhere to the tube surface and form a biofilm, leading to potentially life threatening fu...

    Authors: Yunyun Wei, Jianfeng Qiu, Ziqiang Han, Xuanyi Wang, Hui Zhang, Xinya Hou, Xiangwei Lv and Xiaolong Mao
    Citation: Biomaterials Research 2023 27:97
  25. Biofilm formation on medical device surfaces is a persistent problem that shelters bacteria and encourages infections and implant rejection. One promising approach to tackle this problem is to coat the medical...

    Authors: Cecil Cherian Lukose, Ioannis Anestopoulos, Iraklis-Stavros Panagiotidis, Guillaume Zoppi, Anna M. Black, Lynn G. Dover, Leon Bowen, Ángel Serrano-Aroca, Terence Xiaoteng Liu, Lorenzo Mendola, Davide Morrone, Mihalis I. Panayiotidis and Martin Birkett
    Citation: Biomaterials Research 2023 27:93
  26. Colorectal cancer (CRC) is the second most deadly cancer worldwide, with chemo-resistance remaining a major obstacle in CRC treatment. Notably, the imbalance of redox homeostasis-mediated ferroptosis and the m...

    Authors: Hao Jiang, Hailong Tian, Zhihan Wang, Bowen Li, Rui Chen, Kangjia Luo, Shuaijun Lu, Edouard C. Nice, Wei Zhang, Canhua Huang, Yuping Zhou, Shaojiang Zheng and Feng Gao
    Citation: Biomaterials Research 2023 27:92
  27. Glioblastoma is a highly malignant brain tumor associated with poor prognosis. Conventional therapeutic approaches have limitations due to their toxic effects on normal tissue and the development of tumor cell...

    Authors: Hyung Shik Kim, Jae Hak Seol, Hae Hyun Hwang and Dong Yun Lee
    Citation: Biomaterials Research 2023 27:89
  28. Drug-resistant bacterial infections in chronic wounds are a persistent issue, as they are resistant to antibiotics and can cause excessive inflammation due to generation of reactive oxygen species (ROS). An ef...

    Authors: Jiahui Zhao, Tengfei Xu, Jichao Sun, Haitao Yuan, Mengyun Hou, Zhijie Li, Jigang Wang and Zhen Liang
    Citation: Biomaterials Research 2023 27:88
  29. The global increase of cutaneous wounds imposes huge health and financial burdens on patients and society. Despite improved wound healing outcomes, conventional wound dressings are far from ideal, owing to the...

    Authors: Minxiong Li, Wenzheng Xia, Yi Min Khoong, Lujia Huang, Xin Huang, Hsin Liang, Yun Zhao, Jiayi Mao, Haijun Yu and Tao Zan
    Citation: Biomaterials Research 2023 27:87
  30. Currently, the clinical treatment of critical bone defects attributed to various causes remains a great challenge, and repairing these defects with synthetic bone substitutes is the most common strategy. In ge...

    Authors: Bixia Zhou, Xulei Jiang, Xinxin Zhou, Wuyuan Tan, Hang Luo, Shaorong Lei and Ying Yang
    Citation: Biomaterials Research 2023 27:86
  31. The reconstruction of tendons with large defects requires grafts with high mechanical strength and is often hindered by complications such as infection and adhesion. Hence, grafts combining the advantages of m...

    Authors: Sunfang Chen, Dan Cai, Qi Dong, Gaoxiang Ma, Chennan Xu, Xiaogang Bao, Wei Yuan, Bing Wu and Bin Fang
    Citation: Biomaterials Research 2023 27:85
  32. Bioresorbable stents are designed to provide temporary mechanical support to the coronary arteries and then slowly degrade in vivo to avoid chronic inflammation. Zinc (Zn) is a promising material for bioresorb...

    Authors: Jiayin Fu, Qiongjun Zhu, Zhezhe Chen, Jing Zhao, Shaofei Wu, Meng Zhao, Shihui Xu, Dongwu Lai, Guosheng Fu and Wenbin Zhang
    Citation: Biomaterials Research 2023 27:84
  33. Despite the effectiveness of glucagon-like peptide-1 agonist (GLP-1A) in the treatment of diabetes, its large molecular weight and high hydrophilicity result in poor cellular permeability, thus limiting its or...

    Authors: Seho Kweon, Jun-Hyuck Lee, Seong-Bin Yang, Seong Jin Park, Laxman Subedi, Jung-Hyun Shim, Seung-Sik Cho, Jeong Uk Choi, Youngro Byun, Jooho Park and Jin Woo Park
    Citation: Biomaterials Research 2023 27:83
  34. Human omentum-derived mesenchymal stem cells (hO-MSCs) possess great potential to differentiate into multiple lineages and have self-renewal capacity, allowing them to be utilized as patient-specific cell-base...

    Authors: Ji Hoon Jeong, Ki Nam Park, Joo Hyun Kim, KyungMu Noh, Sung Sik Hur, Yunhye Kim, Moonju Hong, Jun Chul Chung, Jae Hong Park, Jongsoon Lee, Young-Ik Son, Ju Hun Lee, Sang-Heon Kim and Yongsung Hwang
    Citation: Biomaterials Research 2023 27:82
  35. Exosomes are extracellular vesicles secreted by eukaryotic cells and have been extensively studied for their surface markers and internal cargo with unique functions. A deeper understanding of exosomes has all...

    Authors: Eun Sook Lee, Hyewon Ko, Chan Ho Kim, Hyun-Chul Kim, Seong-Kyoon Choi, Sang Won Jeong, Se-Guen Lee, Sung-Jun Lee, Hee-Kyung Na, Jae Hyung Park and Jung Min Shin
    Citation: Biomaterials Research 2023 27:81
  36. Human skin is an organ located in the outermost part of the body; thus, it frequently exhibits visible signs of physiological health. Ethical concerns and genetic differences in conventional animal studies hav...

    Authors: Minjun Ahn, Won-Woo Cho, Wonbin Park, Jae-Seong Lee, Min-Ju Choi, Qiqi Gao, Ge Gao, Dong-Woo Cho and Byoung Soo Kim
    Citation: Biomaterials Research 2023 27:80
  37. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) gain attention as a potent cell source in regenerative medicine and drug discovery. With the necessity of the demands for experimental mod...

    Authors: Huyen T. M. Pham, Duc Long Nguyen, Hyo-Sop Kim, Eun Kyeong Yang, Jae-Ho Kim, Hyun C. Yoon and Hyun-Ji Park
    Citation: Biomaterials Research 2023 27:79
  38. Exosomes are known as nanovesicles that are naturally secreted, playing an essential role in stem-mediated cardioprotection. This study mainly focused on investigating if exosomes derived from miR-214 overexpr...

    Authors: Wenwu Zhu, Qingjie Wang, Jian Zhang, Ling Sun, Xiu Hong, Wei Du, Rui Duan, Jianguang Jiang, Yuan Ji, Haoran Wang and Bing Han
    Citation: Biomaterials Research 2023 27:77
  39. Various joint pathologies such as osteochondritis dissecans, osteonecrosis, rheumatic disease, and trauma, may result in severe damage of articular cartilage and other joint structures, ranging from focal defe...

    Authors: Wenqian Zhang, Kangkang Zha, Weixian Hu, Yuan Xiong, Samuel Knoedler, Doha Obed, Adriana C. Panayi, Ze Lin, Faqi Cao, Bobin Mi and Guohui Liu
    Citation: Biomaterials Research 2023 27:76
  40. Reactive oxygen species (ROS) overproduction and excessive hypoxia play pivotal roles in the initiation and progression of ulcerative colitis (UC). Synergistic ROS scavenging and generating O2 could be a promisin...

    Authors: Ying Zhang, Hengyu Lei, Pengchong Wang, Qinyuan Zhou, Jie Yu, Xue Leng, Ruirui Ma, Danyang Wang, Kai Dong, Jianfeng Xing and Yalin Dong
    Citation: Biomaterials Research 2023 27:75