Click chemistry is termed as a group of chemical reactions with favorable reaction rate and orthogonality. Recently, click chemistry is paving the way for novel innovations in biomedical science, and nanoparti...
Authors: Gawon Yi, Jihwan Son, Jihye Yoo, Changhee Park and Heebeom Koo
The worldwide demand for the organ replacement or tissue regeneration is increasing steadily. The advancements in tissue engineering and regenerative medicine have made it possible to regenerate such damaged o...
In the past decade, stem cells, with their ability to differentiate into various types of cells, have been proven to be resourceful in regenerative medicine and tissue engineering. Despite the ability to repai...
Authors: Ee-Seul Kang, Da-Seul Kim, Intan Rosalina Suhito, Wanhee Lee, Inbeom Song and Tae-Hyung Kim
Lubricin is chondrocyte-secreted glycoprotein that primarily conducts boundary lubrication between joint surfaces. Besides its cytoprotective function and extracellular matrix (ECM) attachment, lubricin is rec...
Authors: Yunsup Lee, Jaehoon Choi and Nathaniel S. Hwang
The purpose of this paper is to provide technology trends and information regarding market and prospects in stents used for human blood vessels in Korea and the world.
Authors: Jeong Hee Lee, Eung Do Kim, Eun Jung Jun, Hyoung Sun Yoo and Joon Woo Lee
Controlled drug delivery system is highly important for not only prolonged the efficacy of drug but also cellular development for tissue engineering. A number of biopolymer composites and nanostructured carrie...
Authors: Sarath Chandra Veerla, Da Reum Kim and Sung Yun Yang
Fetal bovine serum (FBS) is the most essential supplement in culture media for cellular proliferation, metabolism, and differentiation. However, due to a limited supply and subsequently rising prices, a series...
Biomaterials that promote the self-renewal ability and differentiation capacity of neural stem cells (NSCs) are desirable for improving stem cell therapy to treat neurodegenerative diseases. Incorporation of m...
Authors: Jung Seung Lee, Kisuk Yang, Ann-Na Cho and Seung-Woo Cho
The extracellular matrix (ECM) can directly or indirectly influence on regulation of cell functions such as cell adhesion, migration, proliferation and differentiation. The cell derived ECM (CD-ECM) is a usefu...
Zwitterionic molecules have been widely studied as coating materials for preparing anti-fouling surfaces because they possess strong hydration properties that can resist non-specific protein adsorption. Numero...
Authors: Se Yeong Lee, Yunki Lee, Phuong Le Thi, Dong Hwan Oh and Ki Dong Park
The molecular diagnostics market can be broadly divided into PCR (rt-PCR, d-PCR), NGS(Next Generation Sequencing), Microarray, FISH(Fluorescent in situ-hybridization) and other categories, based on the diagnos...
Authors: Ju Hwan Seo, Joon Woo Lee and Daemyeong Cho
Tissue engineering is an interdisciplinary field that attempts to restore or regenerate tissues and organs through biomimetic fabrication of scaffolds with specific functionality. In recent years, graphene oxi...
Authors: Jiyong Kim, Hwan D. Kim, Jungha Park, Eun-seo Lee, Eugene Kim, Seunghun S. Lee, Jin-Kyung Yang, Yoon-Sik Lee and Nathaniel S. Hwang
During pulmonary artery catheter (PAC) implantation, inaccurate measurements of hemodynamic parameters due to infection or thrombosis of PAC can result in severe complications.
Authors: Jung Wook Han, Yeon Soo Shin, Jung Ju Kim and Ho Sung Son
An electrically conductive hydrogel has emerged to regulate cellular secretion activities with electrical stimulation. However, the electrical conductivity of typical hydrogel systems decreases with increasing...
Authors: Ross J. DeVolder, Yongbeom Seo and Hyunjoon Kong
Intervertebral disc degeneration has an annual worldwide socioeconomic impact masked as low back pain of over 70 billion euros. This disease has a high prevalence over the working age class, which raises the s...
Authors: Sebastião van Uden, Joana Silva-Correia, Joaquim Miguel Oliveira and Rui Luís Reis
The three-dimensional (3D) system is one of the important factors to engineer a biocompatible and functional scaffold for the applications of cell-based therapies for cartilage repair. The 3D alginate hydrogel...
Authors: Y. W. Ewa-Choy, B. Pingguan-Murphy, N. A. Abdul-Ghani, J. Jahendran and K. H. Chua
Polyglycerol is an attractive hydrophilic building block of amphiphilic copolymers for biomedical and pharmaceutical applications due to its biocompatibility, facile chemical modification, and anti-fouling act...
Authors: Trang Huyen Le Kim, Hwiseok Jun, Jin Ho Kim, Keunchil Park, Jee Seon Kim and Yoon Sung Nam
Gold nanoclusters (AuNCs) are typically composed of several to tens of gold atoms which are stabilized with biomacromolecules such as bovine serum albumin (BSA). Au NCs fluoresces in the visible to near infrar...
Surface functionalization of orthopedic implants with pharmaceutically active agents is a modern approach to enhance osseointegration in systemically altered bone. A local release of strontium, a verified bone...
Authors: Markus Göttlicher, Marcus Rohnke, Yannik Moryson, Jürgen Thomas, Joachim Sann, Anja Lode, Matthias Schumacher, Romy Schmidt, Stefan Pilz, Annett Gebert, Thomas Gemming and Jürgen Janek
In biomedicine, adhesives for hard and soft tissues are crucial for various clinical purposes. However, compared with that under dry conditions, adhesion performance in the presence of water or moisture is dra...
Authors: Kyu Ha Park, Keum-Yong Seong, Seung Yun Yang and Sungbaek Seo
The injection of botulinum toxin (BTX) to reduce facial wrinkles is one of the most frequently performed plastic surgery procedures. The biocompatible hydrogels are injected with BTX for effective tissue augme...
Authors: Ki Su Kim, Yun Seop Kim, Kai Bao, Hideyuki Wada, Hak Soo Choi and Sei Kwang Hahn
Polymeric micelles attract great attention in drug delivery and therapeutics. Various types of block copolymers have been designed for the application in biomedical fields. If we can introduce additional funct...
Crosslinked gelatin nanofibers are one of the widely used scaffolds for soft tissue engineering. However, modifying the biodegradation rate of chemically crosslinked gelatin is necessary to facilitate cell mig...
Authors: Jae Baek Lee, Young-Gwang Ko, Donghwan Cho, Won Ho Park and Oh Hyeong Kwon
Calcium phosphate (CaP) based nanoparticles are considered to be ideal drug carriers for delivery of anticancer drugs because of their excellent biocompatibility and pH responsiveness. However, CaP nanoparticl...
In this study, silk fibroin (SF) composite hydrogels containing hydroxyapatite (HAP) nanoparticles (NPs) for bone tissue engineering were fabricated using gamma-ray (γ-ray) irradiation treatment. During the ir...
Authors: Min Hee Kim, Beom Su Kim, Jun Lee, Donghwan Cho, Oh Hyeong Kwon and Won Ho Park
