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  1. In recent years, there has been significant research progress on in situ articular cartilage (AC) tissue engineering with endogenous stem cells, which uses biological materials or bioactive factors to improve ...

    Authors: Jiang Wu, Liwei Fu, Zineng Yan, Yu Yang, Han Yin, Pinxue Li, Xun Yuan, Zhengang Ding, Teng Kang, Zhuang Tian, Zhiyao Liao, Guangzhao Tian, Chao Ning, Yuguo Li, Xiang Sui, Mingxue Chen…
    Citation: Biomaterials Research 2023 27:7
  2. Post-traumatic massive hemorrhage demands immediately available first-aid supplies with reduced operation time and good surgical compliance. In-situ crosslinking gels that are flexibly adapting to the wound shape...

    Authors: Qinchao Zhu, Xuhao Zhou, Yanan Zhang, Di Ye, Kang Yu, Wangbei Cao, Liwen Zhang, Houwei Zheng, Ziyang Sun, Chengchen Guo, Xiaoqian Hong, Yang Zhu, Yajun Zhang, Ying Xiao, Teresa G. Valencak, Tanchen Ren…
    Citation: Biomaterials Research 2023 27:6
  3. The tumor microenvironment (TME) is a unique environment that is developed by the tumor and controlled by tumor-induced interactions with host cells during tumor progression. The TME includes immune cells, whi...

    Authors: Minjeong Kim, Na Kyeong Lee, Chi-Pin James Wang, Jaesung Lim, Min Ji Byun, Tae-Hyung Kim, Wooram Park, Dae-Hwan Park, Se-Na Kim and Chun Gwon Park
    Citation: Biomaterials Research 2023 27:5
  4. Obesity, a serious threat to public health, is linked to chronic metabolic complications including insulin resistance, type-2 diabetes, and metabolic dysfunction-associated fatty liver disease (MAFLD). Current...

    Authors: Do Kyung Kim, Daewon Han, Jeongyun Bae, Haeil Kim, Solji Lee, Jong-Seok Kim, Young-Gil Jeong, Jongdae Shin and Hwan-Woo Park
    Citation: Biomaterials Research 2023 27:4
  5. Spinal cord injury (SCI) brings a heavy burden to individuals and society, and there is no effective treatment at present. Exosomes (EX) are cell secreted vesicles containing molecules such as nucleic acids an...

    Authors: Xiao Lu, Guangyu Xu, Zhidi Lin, Fei Zou, Siyang Liu, Yuxuan Zhang, Wei Fu, Jianyuan Jiang, Xiaosheng Ma and Jian Song
    Citation: Biomaterials Research 2023 27:3
  6. The brain vascular basement membrane (brain-VBM) is an important component of the brain extracellular matrix, and the three-dimensional structure of the cerebrovascular network nested with many cell-adhesive p...

    Authors: Wanqing Ji, Zhiru Wu, Jiaming Wen, Hengxin Tang, Zhuopeng Chen, Bo Xue, Zhenming Tian, Yueyang Ba, Ning Zhang, Xuejun Wen and Bo Hou
    Citation: Biomaterials Research 2023 27:2
  7. Plastic surgery is a discipline that uses surgical methods or tissue transplantation to repair, reconstruct and beautify the defects and deformities of human tissues and organs. Three-dimensional (3D) bioprint...

    Authors: Pu Yang, Yikun Ju, Yue Hu, Xiaoyan Xie, Bairong Fang and Lanjie Lei
    Citation: Biomaterials Research 2023 27:1
  8. Distraction osteogenesis (DO) is an efficacious but lengthy procedure to reconstruct segmental bone defects under the principle of tension-stress, during which the periosteum-mediated mechanical stimulation pl...

    Authors: Tengfei Lou, Kai Chen, Qiyu Luo, Changsheng Liu, Yuan Yuan and Cunyi Fan
    Citation: Biomaterials Research 2022 26:91
  9. The restoration of the functional ability of mesenchymal stem cells (MSCs) using epigenetic modification is very promising for patients with weak osteogenesis ability. This study focused on the acceleration of...

    Authors: So Hee Nam, Yan Lee, Chi-Heon Kim, Dong Eun Kim, Hee-Jin Yang and Sung Bae Park
    Citation: Biomaterials Research 2022 26:90
  10. Exosomes derived from bone marrow mesenchymal stem cells (BMSC-exos) have been shown triggering osteogenic differentiation and mineralization of MSCs, but exosomes administered via bolus injections are rapidly...

    Authors: Xuewen Li, Zihao Liu, Shendan Xu, Xinying Ma, Zhezhe Zhao, Han Hu, Jiayin Deng, Cheng Peng, Yonglan Wang and Shiqing Ma
    Citation: Biomaterials Research 2022 26:89
  11. Transepithelial medical devices are increasing utilized in clinical practices. However, the damage of continuous natural epithelial barrier has become a major risk factor for the failure of epithelium-penetrat...

    Authors: Shoucheng Chen, Zhuwei Huang, Rahul Madathiparambil Visalakshan, Haiwen Liu, Akash Bachhuka, You Wu, Panthihage Ruvini L. Dabare, Pu Luo, Runheng Liu, Zhuohong Gong, Yin Xiao, Krasimir Vasilev, Zhuofan Chen and Zetao Chen
    Citation: Biomaterials Research 2022 26:88
  12. Volumetric muscle loss (VML) due to various reasons may cause motor dysfunction and tissue engineering has been proposed for muscle regeneration. However, developing three-dimensional (3D) tissue-engineered sc...

    Authors: Yong Shi, Xiaoxuan Zhang, Rui Liu, Xiaoyan Shao, Yuanjin Zhao, Zhuxiao Gu and Qing Jiang
    Citation: Biomaterials Research 2022 26:87
  13. Coronary artery disease is a cardiovascular disease with a high mortality and mortality rate in modern society. Vascular stent insertion to restore blood flow is essential to treat this disease. A fully biodeg...

    Authors: Seung-Woon Baek, Da-Seul Kim, Duck Hyun Song, Han Byul Kim, Semi Lee, Jun Hyuk Kim, Jun-Kyu Lee, Young Joon Hong, Chun Gwon Park and Dong Keun Han
    Citation: Biomaterials Research 2022 26:86
  14. Engineered living materials (ELMs) combine living cells with non-living scaffolds to obtain life-like characteristics, such as biosensing, growth, and self-repair. Some ELMs can be 3D-printed and are called bi...

    Authors: Bojan Žunar, Taiga Ito, Christine Mosrin, Yoshiyuki Sugahara, Hélène Bénédetti, Régis Guégan and Béatrice Vallée
    Citation: Biomaterials Research 2022 26:85
  15. Microelectrode array (MEA) systems are valuable for in vitro assessment of neurotoxicity and drug efficiency. However, several difficulties such as protracted functional maturation and high experimental costs ...

    Authors: Xiaobo Han, Naoki Matsuda, Yuto Ishibashi, Aoi Odawara, Sayuri Takahashi, Norie Tooi, Koshi Kinoshita and Ikuro Suzuki
    Citation: Biomaterials Research 2022 26:84
  16. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have been found to have a great potential for soft tissue repair due to various biological functions, including pro-angiogenesis and low immunogen...

    Authors: Di Sun, Shan Mou, Lifeng Chen, Jie Yang, Rongrong Wang, Aimei Zhong, Wei Wang, Jing Tong, Zhenxing Wang and Jiaming Sun
    Citation: Biomaterials Research 2022 26:83
  17. Silicone breast implants are commonly used for cosmetic and oncologic surgical indications owing to their inertness and being nontoxic. However, complications including capsular contracture and anaplastic larg...

    Authors: Fatemeh Tavakoli Foroushani, Kevin Dzobo, Nonhlanhla P Khumalo, Vanessa Zamora Mora, Roberto de Mezerville and Ardeshir Bayat
    Citation: Biomaterials Research 2022 26:80
  18. Although the use of cardiac patches is still controversial, cardiac patch has the significance in the field of the tissue engineered cardiac regeneration because it overcomes several shortcomings of intra-myoc...

    Authors: Jung Hee Wee, Ki-Dong Yoo, Sung Bo Sim, Hyun Joo Kim, Han Joon Kim, Kyu Nam Park, Gee-Hee Kim, Mi Hyoung Moon, Su Jung You, Mi Yeon Ha, Dae Hyeok Yang, Heung Jae Chun, Jae Hoon Ko and Chun Ho Kim
    Citation: Biomaterials Research 2022 26:79
  19. Cells in the human body experience different growth environments and conditions, such as compressive pressure and oxygen concentrations, depending on the type and location of the tissue. Thus, a culture device...

    Authors: Seung-Hoon Um, Youngmin Seo, Hyunseon Seo, Kyungwoo Lee, Sun Hwa Park, Jung Ho Jeon, Jung Yeon Lim, Myoung-Ryul Ok, Yu-Chan Kim, Hyunjung Kim, Cheol-Hong Cheon, Hyung-Seop Han, James R. Edwards, Sung Won Kim and Hojeong Jeon
    Citation: Biomaterials Research 2022 26:78
  20. Combination of chemotherapy and immune checkpoint inhibitor therapy has greatly improved the anticancer effect on multiple malignancies. However, the efficiency on triple-negative breast cancer (TNBC) is limit...

    Authors: Hao Wu, Guoli Wei, Lixia Luo, Lingchang Li, Yibo Gao, Xiaobin Tan, Sen Wang, Haoxiao Chang, Yuxi Liu, Yingjie Wei, Jie Song, Zhenhai Zhang and Jiege Huo
    Citation: Biomaterials Research 2022 26:77
  21. β-Secretase (BACE1) is the vital enzyme in the pathogenic processes of Alzheimer's disease (AD). However, the development of a powerful tool with sensitivity for BACE1 determination in vivo is a challenge.

    Authors: Anyao Bi, Junyong Wu, Shuai Huang, Yongjiang Li, Fan Zheng, Jipeng Ding, Jie Dong, Daxiong Xiang and Wenbin Zeng
    Citation: Biomaterials Research 2022 26:76
  22. Control of 3D printing of highly tough hydrogel inks with adequate printability, scaffold fidelity and mechanical properties are highly desirable for biomedical and tissue engineering applications. However, de...

    Authors: Hao Nguyen Tran, In Gul Kim, Jong Heon Kim, Eun-Jae Chung and Insup Noh
    Citation: Biomaterials Research 2022 26:75
  23. Gemcitabine (GEM) is one of the first-line chemotherapies for bladder cancer (BC), but the GEMs cannot recognize cancer cells and have a low long-term response rate and high recurrence rate with side effects d...

    Authors: Wei Xiang, Yongbo Peng, Hongliang Zeng, Chunping Yu, Qun Zhang, Biao Liu, Jiahao Liu, Xing Hu, Wensu Wei, Minhua Deng, Ning Wang, Xuewen Liu, Jianfei Xie, Weibin Hou, Jin Tang, Zhi Long…
    Citation: Biomaterials Research 2022 26:74
  24. Until recent, there are no ideal small diameter vascular grafts available on the market. Most of the commercialized vascular grafts are used for medium to large-sized blood vessels. As a solution, vascular ti...

    Authors: Gi Hoon Yang, Donggu Kang, SangHyun An, Jeong Yeop Ryu, KyoungHo Lee, Jun Sik Kim, Moon-Yong Song, Young-Sik Kim, Sang-Mo Kwon, Won-Kyo Jung, Woonhyeok Jeong and Hojun Jeon
    Citation: Biomaterials Research 2022 26:73
  25. Implant-associated infection (IAI) is increasingly emerging as a serious threat with the massive application of biomaterials. Bacteria attached to the surface of implants are often difficult to remove and exhi...

    Authors: Jiale Dong, Wenzhi Wang, Wei Zhou, Siming Zhang, Meng Li, Ning Li, Guoqing Pan, Xianzuo Zhang, Jiaxiang Bai and Chen Zhu
    Citation: Biomaterials Research 2022 26:72
  26. Glioblastoma multiforme (GBM) is a fatal malignant primary brain tumor in adults. The therapeutic efficacy of chemotherapeutic drugs is limited due to the blood-brain barrier (BBB), poor drug targeting, and sh...

    Authors: Zhipeng Yao, Xiaochun Jiang, Hong Yao, Yafeng Wu, Fan Zhang, Cheng Wang, Chenxue Qi, Chenhui Zhao, Zeyu Wu, Min Qi, Jia Zhang, Xiaoxiang Cao, Zhichun Wang, Fei Wu, Chengyun Yao, Songqin Liu…
    Citation: Biomaterials Research 2022 26:71
  27. Hydrogels show great potential to be used for intraocular applications due to their high-water content and similarity to the native vitreous. Injectable thermosensitive hydrogels through a small-bore needle ca...

    Authors: Kaiwen Zhang, Zengping Liu, Qianyu Lin, Yi Jian Boo, Valerie Ow, Xinxin Zhao, Daniel Soo Lin Wong, Jason Y. C. Lim, Kun Xue, Xinyi Su, Decheng Wu and Xian Jun Loh
    Citation: Biomaterials Research 2022 26:70
  28. Destruction of alveolar bone and periodontal ligament due to periodontal disease often requires surgical treatment to reconstruct the biological construction and functions of periodontium. Despite significant ...

    Authors: Yingming Wei, Zhongxiu Wang, Jiayin Han, Xiaojian Jiang, Lihong Lei, Xianyan Yang, Weilian Sun, Zhongru Gou and Lili Chen
    Citation: Biomaterials Research 2022 26:68
  29. Despite limited efficiency, modulation of microglia/macrophages has shown to attenuate neuroinflammation after intracerebral hemorrhage (ICH). In this context, we evaluated the efficacy of modified exosomal si...

    Authors: Xinjie Gao, Heng Yang, Weiping Xiao, Jiabin Su, Yuwen Zhang, He Wang, Wei Ni and Yuxiang Gu
    Citation: Biomaterials Research 2022 26:67
  30. As an emerging therapeutic modality, chemodynamic therapy (CDT), converting hydrogen peroxide (H2O2) into highly toxic reactive oxygen species (ROS), has been developed for tumor-specific therapy. However, the de...

    Authors: Shuixiu Zhou, Jiahuan Xu, Yanfei Dai, Yan Wei, Liang Chen, Wei Feng, Yu Chen and Xuejun Ni
    Citation: Biomaterials Research 2022 26:66
  31. Recently, nanocarriers, including micelles, polymers, carbon-based materials, liposomes, and other substances, have been developed for efficient delivery of drugs, nucleotides, and biomolecules. This review fo...

    Authors: Naline Bellier, Phornsawat Baipaywad, Naeun Ryu, Jae Young Lee and Hansoo Park
    Citation: Biomaterials Research 2022 26:65
  32. It is highly desirable to develop new therapeutic strategies for gastric cancer given the low survival rate despite improvement in the past decades. Cadherin 17 (CDH17) is a membrane protein highly expressed i...

    Authors: Jingbo Ma, Xiaolong Xu, Chunjin Fu, Peng Xia, Ming Tian, Liuhai Zheng, Kun Chen, Xiaolian Liu, Yilei Li, Le Yu, Qinchang Zhu, Yangyang Yu, Rongrong Fan, Haibo Jiang, Zhifen Li, Chuanbin Yang…
    Citation: Biomaterials Research 2022 26:64
  33. Hostile environment around the lesion site following spinal cord injury (SCI) prevents the re-establishment of neuronal tracks, thus significantly limiting the regenerative capability. Electroconductive scaffo...

    Authors: Aleksandra Serafin, Mario Culebras Rubio, Marta Carsi, Pilar Ortiz-Serna, Maria J. Sanchis, Atul K. Garg, J. Miguel Oliveira, Jacob Koffler and Maurice N. Collins
    Citation: Biomaterials Research 2022 26:63
  34. Overproduction of reactive oxygen species (ROS) is known to delay wound healing by causing oxidative tissue damage and inflammation. The green tea catechin, (–)-Epigallocatechin-3-O-gallate (EGCG), has drawn a gr...

    Authors: Gyeongwoo Lee, Young-Gwang Ko, Ki Hyun Bae, Motoichi Kurisawa, Oh Kyoung Kwon and Oh Hyeong Kwon
    Citation: Biomaterials Research 2022 26:62
  35. Wound closure in the complex body environment places higher requirements on suture’s mechanical and biological performance. In the scenario of frequent mechanical gastric motility and extremely low pH, single ...

    Authors: Zhaohui Luan, Shuang Liu, Wei Wang, Kaige Xu, Shaosong Ye, Ruijue Dan, Hong Zhang, Zhenzhen Shu, Tongchuan Wang, Chaoqiang Fan, Malcolm Xing and Shiming Yang
    Citation: Biomaterials Research 2022 26:60
  36. In an aging society, quality of life improvement is emerging as an important issue, and as implants are accepted as the core of oral rehabilitation treatment, competition for leadership in developing related t...

    Authors: Woo Jin Kim, Young-Dan Cho, Young Ku and Hyun-Mo Ryoo
    Citation: Biomaterials Research 2022 26:59
  37. Recombinant tissue plasminogen activator (rtPA) has a short half-life, and additional hemorrhagic transformation (HT) can occur when treatment is delayed. Here, we report the design and thrombolytic performanc...

    Authors: Wonseok Choi, Hyeyoun Cho, Gahee Kim, Inchan Youn, Jaehong Key and Sungmin Han
    Citation: Biomaterials Research 2022 26:58
  38. Optical imaging has been essential for scientific observations to date, however its biomedical applications has been restricted due to its poor penetration through tissues. In living tissue, signal attenuation...

    Authors: Seokchan Yoon, Seo Young Cheon, Sangjun Park, Donghyun Lee, Yeeun Lee, Seokyoung Han, Moonseok Kim and Heebeom Koo
    Citation: Biomaterials Research 2022 26:57
  39. Photodynamic therapy (PDT) is a promising strategy to promote antitumor immunity by inducing immunogenic cell death (ICD) in tumor cells. However, practical PDT uses an intense visible light owing to the shall...

    Authors: Jiwoong Choi, Il Seong Lee, Ju Seung Lee, Sangmin Jeon, Wan Su Yun, Suah Yang, Yujeong Moon, Jinseong Kim, Jeongrae Kim, Seunghwan Choy, Chanho Jeong, Man Kyu Shim, Tae-il Kim and Kwangmeyung Kim
    Citation: Biomaterials Research 2022 26:56
  40. To support bone regeneration, 3D-printed templates function as temporary guides. The preferred materials are synthetic polymers, due to their ease of processing and biological inertness. Poly(lactide-co-trimet...

    Authors: Mohamad Nageeb Hassan, Mohammed Ahmed Yassin, Ahmed Maher Eltawila, Ahmed Emad Aladawi, Samih Mohamed-Ahmed, Salwa Suliman, Sherif Kandil and Kamal Mustafa
    Citation: Biomaterials Research 2022 26:55
  41. The gelatin-methacryloyl (GelMA) polymer suffers shape fidelity and structural stability issues during 3D bioprinting for bone tissue engineering while homogeneous mixing of reinforcing nanoparticles is always...

    Authors: Amitava Bhattacharyya, Gopinathan Janarthanan, Taeyang Kim, Shiva Taheri, Jisun Shin, Jihyeon Kim, Hyun Cheol Bae, Hyuk-Soo Han and Insup Noh
    Citation: Biomaterials Research 2022 26:54
  42. Dissolving microneedle (DMN) is a transdermal drug delivery system that creates pore in the skin and directly deliver drug through the pore channel. DMN is considered as one of the promising system alternative...

    Authors: Youseong Kim, Hye Su Min, Jiwoo Shin, Jeehye Nam, Geonwoo Kang, Jeeho Sim, Huisuk Yang and Hyungil Jung
    Citation: Biomaterials Research 2022 26:53
  43. Osteoarthritis (OA) is a degenerative joint disease that is common among the middle-aged and older populations, causes patients to experience recurrent pain in their joints and negatively affects their quality...

    Authors: Han Yin, Muzhe Li, Guangzhao Tian, Yang Ma, Chao Ning, Zineng Yan, Jiang Wu, Qian Ge, Xiang Sui, Shuyun Liu, Jinxuan Zheng, Weimin Guo and Quanyi Guo
    Citation: Biomaterials Research 2022 26:52
  44. Due to the deep tissue penetration and reduced scattering, NIR-II fluorescence imaging is advantageous over conventional visible and NIR-I fluorescence imaging for the detection of bone growth, metabolism, met...

    Authors: Haoran Wang, Homan Kang, Jason Dinh, Shinya Yokomizo, Wesley R. Stiles, Molly Tully, Kevin Cardenas, Surbhi Srinivas, Jason Ingerick, Sung Ahn, Kai Bao and Hak Soo Choi
    Citation: Biomaterials Research 2022 26:51
  45. Wound healing is a dynamic series of interconnected events with the ultimate goal of promoting neotissue formation and restoration of anatomical function. Yet, the complexity of wound healing can often result ...

    Authors: Jacob G. Hodge, David S. Zamierowski, Jennifer L. Robinson and Adam J. Mellott
    Citation: Biomaterials Research 2022 26:50
  46. Antisense oligonucleotides (ASOs) are an important tool for the treatment of many genetic disorders. However, similar to other gene drugs, vectors are often required to protect them from degradation and cleara...

    Authors: Si Huang, Xin-Yan Hao, Yong-Jiang Li, Jun‑Yong Wu, Da-Xiong Xiang and Shilin Luo
    Citation: Biomaterials Research 2022 26:49