Fig. 2From: Current strategies for treatment of intervertebral disc degeneration: substitution and regeneration possibilitiesCascade of events associated with IDD morphological signs. Starting by a contribution of an acute or a repeated set of acute loading forces that, as tissue aging progresses, becomes lighter to set IDD. The highlighted areas divide the events by tissue/groups of tissue – Red: IVD; Green: NP; Blue: AF and cartilaginous endplates. NP: nucleus pulposus; AF: annulus fibrosus; IVD: intervertebral disc; CEP: cartilaginous endplates; IDD: IVD degeneration diseaseBack to article page