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Fig. 2 | Biomaterials Research

Fig. 2

From: Current strategies for treatment of intervertebral disc degeneration: substitution and regeneration possibilities

Fig. 2

Cascade of events associated with IDD morphological signs. Starting by a contribution of an acute or a repeated set of acute loading forces that, as tissue aging progresses, becomes lighter to set IDD. The highlighted areas divide the events by tissue/groups of tissue – Red: IVD; Green: NP; Blue: AF and cartilaginous endplates. NP: nucleus pulposus; AF: annulus fibrosus; IVD: intervertebral disc; CEP: cartilaginous endplates; IDD: IVD degeneration disease

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