Table 6 Hybridization for EV engineering
From: Recent advances in extracellular vesicle engineering and its applications to regenerative medicine
No. | Components for hybridization | Method | Purpose | Ref. |
|---|---|---|---|---|
1 | EVs / LNP | Incubation | miRNAs encapsulation | [22] |
2 | EVs / LNP | Incubation | miRNAs encapsulation, Targeting, Circulation | [128] |
3 | EVs / LNP | PEG incubation | Drug encapsulation, Circulation | [129] |
4 | EVs / LNP | Sonication | miRNAs encapsulation | [130] |
5 | EVs / LNP | Freeze and thaw | Drug encapsulation, Targeting, Circulation | [131] |
6 | EVs / LNP | Freeze and thaw | Drug encapsulation, Circulation | [138] |
7 | EVs / LNP | Freeze and thaw | Drug encapsulation, Targeting, Circulation | [139] |
8 | EVs / LNP | Freeze and thaw | Drug encapsulation Targeting Circulation | [141] |
9 | EVs / LNP | Freeze and thaw | Drug encapsulation Circulation, Targeting | [140] |
10 | EVs / NVs | Freeze and thaw | Drug encapsulation, Circulation, Targeting | [19] |
11 | EVs / LNP | Extrusion | miRNAs encapsulation, Targeting | [132] |
12 | EVs / LNP | Extrusion | Drug encapsulation, Targeting | [146] |
13 | EVs / Cell membrane | Extrusion | Targeting | [147] |
14 | EVs / LNP | Extrusion | Drug encapsulation, Circulation, Targeting | [142] |
15 | EVs / Nanoghost | Extrusion | siRNAs encapsulation, Circulation | [143] |
16 | EVs / LNP | Extrusion | siRNAs encapsulation, Circulation | [144] |
17 | EVs / LNP | Extrusion after Incubation | Drug encapsulation, Circulation, Targeting | [148] |
18 | EVs /Cell membrane | Extrusion after Incubation | Circulation, Targeting | [20] |
19 | EVs / LNP | Extrusion after Sonication | miRNAs encapsulation, Targeting, Circulation | [149] |
20 | EVs / LNP | Extrusion after Sonication | Drug encapsulation, Targeting, Circulation | [23] |
21 | EVs / LNP | Extrusion after Sonication | Drug encapsulation, Targeting, Circulation | [150] |
22 | EVs / LNP | Extrusion after Sonication | Drug encapsulation, Circulation, Targeting | [151] |
23 | EVs / LNP | Extrusion after Sonication | Drug encapsulation, Circulation, Targeting | [152] |
24 | EVs / LNP | Extrusion after Sonication | Drug encapsulation Targeting | [153] |
25 | EVs / LNP | Extrusion after Sonication | Drug encapsulation, Circulation, Targeting | [155] |
26 | EVs / NV | Extrusion after Sonication | Drug encapsulation, Targeting | [158] |
27 | EVs / LNP | EtOH | Drug encapsulation, Targeting | [156] |
28 | EVs / EVs | Metal-phenolic coordination | Drug encapsulation | [157] |