Recent advances in extracellular vesicle engineering and its applications to regenerative medicine

Biomaterials Research

Table 3 Cell preconditioning with inflammatory factors for EV engineering

No.	Target cell	Treatment material	Concentration	Ref.
1	UCMSC	IFN-γ	50 ng/ml	[65]
2	GMSC	TNF-α	10 ng/ml	[66]
3	BMSC	TNF-α, IFN-γ	15 ng/ml; 10 ng/ml	[67]
4	BMSC	TNF-α, IFN-γ	20 ng/ml; 20 ng/ml	[68]
5	UCMSC	TNF-α, IFN-γ	20 ng/ml; 20 ng/ml	[69]
6	UCMSC	TNF-α, IFN-γ	20 ng/ml; 20 ng/ml	[21]
7	UCMSC	TNF-α, IFN-γ	20 ng/ml; 20 ng/ml	[70]
8	GMSC	TNF-α, IFN-α	50 ng/ml; 50 ng/ml	[72]
9	BMSC	IL-1β	10 ng/ml	[73]
10	BMSC	IL-1β	10 ng/ml	[74]
11	BMSC	LPS	100 ng/ml	[75]
12	BMSC	LPS	100 ng/ml	[76]

ISSN: 2055-7124