Fig. 7
From: Recent advances in extracellular vesicle engineering and its applications to regenerative medicine
Endogenous modification methods for EV engineering using non-inflammation related factors. A The production process of EVs derived from gemfibrozil preconditioned RAW264.7 and their therapeutic pathway for AD. Reproduced with permission from [77]. Copyright 2022 Elsevier. B The functional enhancement and the production process of melatonin preconditioned ADMSC derived EV. Reproduced with permission from [87]. Copyright 2021 SAGE Publications. C The production process of EV derived from cartilage differentiation process with TGF-β3. Reproduced with permission from [15]. Copyright 2022 Springer Nature. D The surface engineering method for EVs using click chemistry with N-azidoacetylmannosamine-tetraacetylated (Ac4ManNAz) treatments. Reproduced with permission from [92]. Copyright 2021 AAAS