Fig. 9
From: Tumor-derived systems as novel biomedical tools—turning the enemy into an ally
Tumor-derived EVs as a diagnostic agent. A Metastasis detection and monitoring of prostate cancer progression using the PCa EV Digital Scoring Assay. Adapted with permission from [194], (Copyright Elsevier, 2023). B Schematic illustration depicting the design of the NanoVilli Chip, which takes inspiration from natural biological structures. The chip incorporates densely packed arrays of silicon nanowires that have been grafted with anti-EpCAM antibodies. This design enables the chip to achieve remarkably efficient and reproducible immunoaffinity capture of tumor-derived EVs. Adapted with permission from [195], (Copyright American Chemical Society, 2019)