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Fig. 6 | Biomaterials Research

Fig. 6

From: Axon guidance gene-targeted siRNA delivery system improves neural stem cell transplantation therapy after spinal cord injury

Fig. 6

Knockdown of Sema3A can improve synaptic connectivity between grafted NSCs and host neurons after SCI. (A-G) Immunofluorescence analysis in merged images of transverse sections stained for GFP-labeled NSCs (anti-GFP, Green), neurons (anti-Tuj1, Red), and nuclei (DAPI, Blue) or synapse (anti-Homer, White). (A) Representative composite tiled scan merged images of GFP and GFAP in the SCI + NSC + siRNA-Sema3A group. (B-D) Higher magnification for GFP, Tuj1, and DAPI (B) ahead of the proximal border (PB), (C) at the grafted site, and (D) in the distal border (DB) from A. (E-G) Higher magnification for GFP, Tuj1, and Homer in the boxed area (E) from B, (F) from C, and (G) from D

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Biomaterials Research

ISSN: 2055-7124

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