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Fig. 5 | Biomaterials Research

Fig. 5

From: Axon guidance gene-targeted siRNA delivery system improves neural stem cell transplantation therapy after spinal cord injury

Fig. 5

Knockdown of Sema3A increases survival of grafted NSCs and induces neural differentiation after transplantation in the injured spinal cord. Immunofluorescence analysis in composite tiled scans of transverse sections stained for GFP-labeled NSCs (anti-GFP, Green) and glial scar (anti-GFAP, Red). (A, B) Representative merged image for GFP and GFAP in the (A) SCI + NSC group, and (B) SCI + NSC + siRNA-Sema3A group. (C, D) Higher magnification in the LC (boxed area) (C) from A and (D) from B. (E, F) Higher magnification of the AS (boxed area) (E) from A and (F) from B

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