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Fig. 2 | Biomaterials Research

Fig. 2

From: Axon guidance gene-targeted siRNA delivery system improves neural stem cell transplantation therapy after spinal cord injury

Fig. 2

Differentiating NSCs express Sema3A, and AuNP@siRNA-Sema3A suppresses Sema3A expression (A-D) Representative immunofluorescence images of Sema3A (anti-Sema3A, Green), neurons (anti-Tuj1, Red), and nuclei (DAPI, Blue) of the (A) non-treated, (B) AuNP, (C) Hydrogel, and (D) AuNP@siRNA-Sema3A groups. (E) Quantitative analyses of the fluorescence intensity for Sema3A. (F-I) Representative immunofluorescence images for Tuj1-labelled axon growth of the (F) non-treated group, (G) AuNP, (H) Hydrogel, and (I) AuNP@siRNA-Sema3A groups. (J) Quantitative analyses of Tuj1-labelled total axon growth in ROIs. Results are the mean ± standard error of the mean (SEM); ***p < 0.001. one-way ANOVA with Tukey post-hoc test

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Biomaterials Research

ISSN: 2055-7124

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