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Fig. 1 | Biomaterials Research

Fig. 1

From: Axon guidance gene-targeted siRNA delivery system improves neural stem cell transplantation therapy after spinal cord injury

Fig. 1

(A) Schematic illustration of the synthesis of AuNP@siRNA-Sema3A using electrostatic interactions. TEM images of (B) AuNP, (C) AuNP-PLL, and (D) AuNP@siRNA-Sema3A. (E) Changes in the surface charge of each AuNP according to the step-by-step coating of PLL and siRNA-Sema3A. (F) Confocal micrograph of NSCs treated with Cy5.5-labeled AuNP@siRNA-Sema3A (left) and details (right) of the internalization of Cy5.5-labeled AuNP@siRNA-Sema3A into the cells

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