Fig. 9

Self-healing wound dressings for motional wound. A Tannic acid (TA) was used as a multi-functional H-bond supplier to create a GelMA-based double-network (DN) hydrogel with versatile capabilities. The preparation of a versatile GelMA-TA hydrogel (a) with high stiffness, super-elasticity, deformability (b), and in vivo self-healing and adhesive properties is shown schematically (c). GelMA-TA gel has been used in biomedical applications such as skin wound closure (d), sutureless gastric surgery (e), and as a strain sensor when MWCNTs are present (f). Reprinted with permission from ref [69]. Copyright 2018 Elsevier. B Antibacterial adhesive injectable hydrogels with quick self-healing, extensibility, and compressibility were manufactured as wound dressing for joints skin wound healing by mixing quaternized chitosan (QCS) and benzaldehyde-terminated Pluronic®F127 (PF127-CHO) under physiological conditions. (a) Schematic presentation of the hydrogel and TEM images. Scale bar: 200 nm. (b) Rhodamine B coloured QCS/PF1.0 hydrogels in their natural bending, compression, stretching, twisting, and knotting shapes. Scale bar: 1 cm. Reprinted with permission from ref [146]. Copyright 2018 Elsevier