Fig. 6

Wound dressings with anti-inflammation function. A Curcumin was delivered via a thermosensitive hydrogel containing the nanodrug in the form of gelatin microspheres (GMs) (Cur) to improves diabetic wound healing. (a) Solution exchange method for producing pure CNPs. (b) The emulsion process loads CNPs into GMs, resulting in CNPs@GMs. (c) In diabetic mice, CNPs@GMs were combined with a thermos-sensitive hydrogel and applied to the wound. (d) GMs were destroyed by MMPs in the microenvironment of a nonhealing wound, and the medication was precisely released. Reprinted with permission from ref [117]. Copyright 2018 American Chemical Society. B Electroactive and antioxidative scaffold was fabricated for wound healing. (a) PDA’s synthetic approach decreased and functionalized pGO. (b) The pGO-CS/SF scaffold is formed with dual cross-links. (c) The skin wound defect was repaired using the scaffold. During wound healing, the scaffold exhibits antioxidative properties and electrical stimulation of the skin tissue. Reprinted with permission from ref [118]. Copyright 2019 American Chemical Society. C Using an efficient and simple one-step technique, ultrasmall Cu5.4O NPs (Cu5.4O USNPs) were created as nanozymes with numerous enzyme-mimicking and widening ROS scavenging capacity against broad ROS-related illnesses, including acute kidney injury, acute liver injury and diabetic wound healing. Reprinted with permission from ref [66]. Copyright 2019 American Chemical Society