Fig. 5

Wound dressings with antibacterial function. A PDA-coated gold nanorods (GNRs) were used to create a chemo-photothermal therapy platform. (a) Schematic of material synthesis; (b) Schematic of charge reversal and Ag + ion release as a result of acidity; (c) Schematic of bacterial-specific targeting and chemo-photothermal combo treatment. Reprinted with permission from ref [94]. Copyright 2018 Springer Nature. B Schematic representation of a self-healing hydrogel dressing which was conductive and adhesive using Pluronic F127/carbon nanotubes (PF127/CNT) and N-carboxyethyl chitosan (CEC). Reprinted with permission from ref [102]. Copyright 2020 Elsevier. C The drug reservoir was made by mixing ciprofloxacin (Cip, a strong antibiotic)-loaded PDA NPs and glycol chitosan (GC) to generate an injectable hydrogel (PDA NP-Cip/GC hydrogel, dubbed Gel-Cip). Reprinted with permission from ref [103]. Copyright 2018 Elsevier. D Gold nanoclusters modified zirconium-based porphyrin metal–organic frameworks (Au NCs@PCN) were designed for Infected Diabetic Wound Healing. (a) Diagram of the Au NCs@PCN fabrication method; (b) High-temperature death of multidrug resistance bacteria under NIR radiation by CDT, PDT, and PTT; (c) Bactericidal via altering bacterial membrane structure and encouraging angiogenesis and epithelial cell healing by upregulating the expression of associated factors. Reprinted with permission from ref [65]. Copyright 2022 American Chemical Society