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Fig. 5 | Biomaterials Research

Fig. 5

From: Disease-microenvironment modulation by bare- or engineered-exosome for rheumatoid arthritis treatment

Fig. 5

A Schematic illustration of RA treatment using M2 macrophage-derived exosomes, M2-EVs, (up) and preparation strategy (down). B Immunofluorescence images of inflamed joint post-injection of saline, MTX, and M2-EVs. C Ex vivo organ distribution images after footpad injection of saline and M2-EVs. D Clinical score and paw thickness of collagen-induced arthritis (CIA) mice after treatment of the samples. E Conventional and thermal images of hind paws in various treatment groups [168]. Reproduced with permission, Copyright 2022, Elsevier

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Biomaterials Research

ISSN: 2055-7124

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