Fig. 3
From: Emerging nano-scale delivery systems for the treatment of osteoporosis
SEM image showing the cell attachment and proliferation of OBs on different concentrations of ZOL-loading scaffolds. OBs exhibited increased morphological elongation and filamentous filopodia at concentrations of 1 µmol/L to 50 µmol/L (Fig. 6). However, at concentrations of 100 µmol/L and 500 µmol/L, cell attachment to the scaffold decreased, resulting in atrophy and reduced pseudopodium formation. OB: Osteoblast; OC: Osteoclast. Reproduced with permission from Yang et al. [73]. (Copyright 2020, IOP Publishing Ltd.)