Fig. 7From: Restoration of dysregulated intestinal barrier and inflammatory regulation through synergistically ameliorating hypoxia and scavenging reactive oxygen species using ceria nanozymes in ulcerative colitisIn vivo inhibition of M1 macrophages activation induced by PEG-CNPs. Pro-inflammatory cytokines a IL-1β and b TNF-α levels and anti-inflammatory cytokines c IL-10 and d TGF-β1 levels with PEG-CNPs treatment in the colon tissues (n = 10). Pro-inflammatory cytokines e IL-1β and f TNF-α levels with PEG-CNPs treatment in the blood serum (n = 10). g Immunohistochemical analysis of CD86 of colon tissues from healthy or TNBS-colitis mice (n = 3). h Statistical analysis of CD86 in immunohistochemical staining (n = 3). The SOD activity i and the MDA level j with PEG-CNPs (n = 10). Data represent means ± s.d. ###P < 0.001 vs. control group; **P < 0.01, ***P < 0.001 vs. TNBS groupBack to article page