Fig. 3
From: Exosomes derived from mir-214-3p overexpressing mesenchymal stem cells promote myocardial repair
Distribution of miR-214-loaded exosomes in infarcted hearts. (A) Flow chart of in vivo experiment design. (B-C) The expression level of CD31 (B) and α-actin (C) protein was detected by immunofluorescence 6 h after intramyocardial injection of Dil labeled exosomes. The white arrow indicate the injection site. The yellow arrow indicates that exosomes were absorbed by endothelial cells and cardiomyocytes. Yellow squares indicate the region near exothelium and yellow boundaries show the region near myocardium. Scale bar = 50 μm. (D) FISH analysis in infarcted LV myocardium of SD Rats. Cy3-miR-214 probe (red) was used to detect miR-214. Concentrated miR-214 was indicated by yellow arrowheads. Scale bar = 20 μm