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Fig. 7 | Biomaterials Research

Fig. 7

From: Open source board based acoustofluidic transwells for reversible disruption of the blood–brain barrier for therapeutic delivery

Fig. 7

SAW expanded intercellular space of hBMECs. hBMECs were seeded on round slides for 48 h to firm barrier, then exposed on a 19.68 MHz SAW at 37.8 dBm for 5 min. The slides were subjected to immunofluorescence staining. The distribution of tight junction proteins was hybridized with the corresponding anti-Occludin (A) or anti-ZO-1 (B) antibody. Nuclei was marked with Hochest 33,342 and shown in blue. The representative image of two independent experiments were shown. Scale bar was 10 μm

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