Fig. 5
The in vivo effects of sonoperfusion and local O2 therapy by OMB treatment in murine S/R model. A The percentage of blood flow and pO2 at the periods of pre, during, and post OMB treatment (termed pre, T, and post, respectively). B Assessment of infarct size in different brain tissue sections. Staining with 2% TTC shows brain infarction as white areas. The blue dotted outline marks the infarct areas. The quantified results present the percentage of infarct area within the whole brain. The plus ( +) symbol represents US sonication. N = 5/group. Significant differences are indicated: *p < 0.05, **p < 0.01, by one-way ANOVA with Bonferroni's multiple comparisons test