Fig. 2
In vitro disruption of OMBs for O2 release. A The size distribution of CMBs and OMBs. B The destruction threshold of MBs under various acoustic pressures. US B-mode images of OMBs show contrast enhancement at an acoustic pressure of 200 kPa, but no enhancement at 300 kPa, defining the destruction threshold of OMB. C pO2 levels after OMB destruction by US with acoustic pressure of 300 kPa. The plus ( +) symbol presents US sonication. The concentration of CMBs and OMBs is 2 × 107 MBs/mL. D Enhanced pO2 levels with increased doses of OMBs. Significant differences are indicated: *p < 0.05, **p < 0.01, by one-way ANOVA with Bonferroni's multiple comparisons test