Fig. 12

Basic schematic of Acousto fluidic Interferometric Device (AID). Acoustic reflectors could be lined on both sides of the microfluidic channel, further lined by mirror on bottom side and placed in close contact with the acoustic transducers such as piezoelectric arrays. The acoustic wave from the transducer forms an acoustic plane, thereby aiding in the mechanical alignment of the inflowing cells. When coupled with an interferometer, fringe patterns could be observed and from this data, the physical properties of cells could be interpreted