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Fig. 5 | Biomaterials Research

Fig. 5

From: A dual functional Ti-Ga alloy: inhibiting biofilm formation and osteoclastogenesis differentiation via disturbing iron metabolism

Fig. 5

Ti-Ga alloys inhibited RANKL-dependent osteoclastogenesis in vitro targeting iron metabolism. (A) Representative images of TRAP staining. BMMs were stimulated with RANKL (50 ng mL− 1) in the absence or presence of extracts of Ti and Ti-Ga alloys, respectively. (B) Representative images of F-actin ring formation in osteoclasts treated with pure Ti and Ti-Ga alloy extracts, respectively. (C) Representative SEM images of bone resorption after treatment with extracts of pure Ti and Ti-Ga alloys respectively.

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