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Fig. 2 | Biomaterials Research

Fig. 2

From: Gelatin methacryloyl (GelMA) loaded with concentrated hypoxic pretreated adipose-derived mesenchymal stem cells(ADSCs) conditioned medium promotes wound healing and vascular regeneration in aged skin

Fig. 2

Wounds in aged skin healed more slowly than that in young skin and exhibit poorer perfusion. A. The image of wounds closure of young and old groups at day 0, 6, 12. Scale bar = 1 cm. B. H&E staining of wound site of young and old groups at day 12. Scale bar = 100 μm. C. The blood perfusion at the wound areas of both groups were evaluated by a laser Doppler perfusion imaging system. D. Immunohistochemical staining of CD31 in regenerated skin tissue. Scale bar = 50 μm. E. Quantitative analysis of relative mean density of immunohistochemical staining of CD31 in regenerated skin tissue. The results are presented as mean ± SD (***P<0.001).

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