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Fig. 3 | Biomaterials Research

Fig. 3

From: Drug-loaded microbubble delivery system to enhance PD-L1 blockade immunotherapy with remodeling immune microenvironment

Fig. 3

The co-polarization effect of R837 and DTX. a FCM results of the expression of M1-phenotype (CD86) and M2-phenotype (CD206) macrophages after different treatments. b-c Quantifications of M1-phenotype and M2-phenotype TAMs. d-e Cytokine secretion levels of IL-12 and IL-10 tested by ELISA. f-g FCM results of M0-to-M1 polarization and quantitative analysis of M1-phenotype macrophages. Data are expressed as mean ± SD (n = 3). Statistical significances were calculated via Student’s t test, *p < 0.05, **p < 0.01 and ***p < 0.001

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