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Fig. 4 | Biomaterials Research

Fig. 4

From: A drug delivery system constructed by a fusion peptide capturing exosomes targets to titanium implants accurately resulting the enhancement of osseointegration peri-implant

Fig. 4

EXO-PEP3 enhanced osteogenesis of BMSCs thanks to targeting to the titanium surface in vitro. A The alizarin red staining determined to the mineralization of cultured BMSCs (P < 0.05). B The quantity analysis of the alizarin red staining. C The RNAs expression involved in the osteogenesis of the BMSCs. The significant differences are calculated by comparing each group each other. D Immunofluorescent staining for a) BMP2 and b) OPN in BMSCs cultured on titanium discs with different treatment. (P < 0.05) FITC: BMP2 or OPN; DAPI: nuclear; Merge: the merge images of FITC and DAPI

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