Fig. 3
From: Targeting treatment of bladder cancer using PTK7 aptamer-gemcitabine conjugate
CCK-8 assays of PTK7-GEMs cytotoxicity. A, B Viability of 5637 cells and SV-HUC-1 cells respectively treated with LIB-GEMs, GEM or PTK7-GEMs evaluated by CCK8 assay. C IC50 of PTK7-GEMs and GEM against 5637 cells (NS, not significant). Data represents the mean ± SEM, n = 3. D, E Cell cycle distributions of 5637 and SV-HUC-1 cells treated with LIB-GEMs, GEM or PTK7-GEMs respectively for 8 h and then incubated for 72 h with complete medium before being tested using flow cytometry