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Fig. 3 | Biomaterials Research

Fig. 3

From: Implantable micro-scale LED device guided photodynamic therapy to potentiate antitumor immunity with mild visible light

Fig. 3

Therapeutic efficacy of micro-LED guided PDT. (a) Noninvasive NIRF images of murine colon tumor models treated with VPF (4 mg/kg). Right panel indicates fluorescence images of tumor tissues from mice after 3 h of VPF treatment. (b) Optical images of mice implanted with micro-LED for local visible light iradiation of tumor tissues. (c) Tumor growth of murine colon tumor models during micro-LED guided PDT at different light intensities. Right panel indicates optical images showing tumor volumes and collected tumor tissues of mice on day 14 after treatment. (d) Tumor tissues stained with TUNEL on day 14 after treatment. Significance was determined by Tukey − Kramer posthoc test

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Biomaterials Research

ISSN: 2055-7124

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