Fig. 7

Construction of si-Tgfbr1-loading liposomes and evaluations in vitro. A flowchart of liposome preparation and evaluation; B TEM imaging of blank liposome and si-Tgfbr1-loading liposomes. Bar = 100 nm; C stability of liposomes in PBS for 24 h; D Polydispersity index and Zeta potential of liposomes; E Toxicity of liposomes evaluated by CCK-8 assay in vitro. NIH3T3 cells were cultured with si-Tgfbr1-loading liposomes under gradient concentrations for 12 h or under 200 nM for 24 h. *: P < 0.05; ****: P < 0.0001