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Table 2 Histological evaluation system: cell type/response

From: Biocompatibility evaluation of peo-treated magnesium alloy implants placed in rabbit femur condyle notches and paravertebral muscles

Cell Type/Response

Score

0

1

2

3

4

Polymorphonuclear cells

0

Rare, 1–5/phfa

5–10/phf

Heavy infiltrate

Packed

Lymphocytes

0

Rare, 1–5/phf

5–10/phf

Heavy infiltrate

Packed

Plasma cells

0

Rare, 1–5/phf

5–10/phf

Heavy infiltrate

Packed

Macrophages

0

Rare, 1–5/phf

5–10/phf

Heavy infiltrate

Packed

Giant cells

0

Rare, 1–5/phf

5–10/phf

Heavy infiltrate

Packed

Necrosis

0

Minimal

Mild

Moderate

Severe

Neovascularisation

0

Minimal capillary proliferation, focal, 1–3 buds

Groups of 4–7 capillaries with supporting fibroblastic structures

Broad band of capillaries with supporting structures

Extensive band of capillaries with supporting fibroblastic structures

Fibrosis

0

Narrow band

Moderately thick band

Thick band

Extensive band

Fatty infiltrate

0

Minimal amount of fat associated with fibrosis

Several layers of fat and fibrosis

Elongated and broad accumulation of fat cells about the implant site

Extensive fat completely surrounding the implant

  1. a phf = per high powered (400 ×) field