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Table 1 Research publication in the recent years of hydrogel for cancer treatment

From: Enhanced postoperative cancer therapy by iron-based hydrogels

Host material

Existence

Function

Indication

Treatment strategy

Ref.

Chitosan-catechol based hydroge

Fe3+

realizing cohesive interaction and sequential release of drug

Lung and breast cancer

Chemotherapy

[96]

Magnetic supramolecular hydrogel

Fe3O4

thermally inducing cell damage; realizing triggered releasing of chemo- therapeutic drugs

breast cancer

MHT-Chemotherapy

[97]

Citrate-iron hydrogel scaffold

Fe3+

photothermal response; decreasing the inflammation response; improving angiogenesis; tissue regeneration

skin cancer

PTT

[98]

PEGDA and AIPH

BGN-Fe-Ag2S

photothermal effect and chemodynamic effect; eliminating multidrug resistant bacteria; accelerating wound healing

breast cancer

PTT-CDT

[99]

Chitosan-based dynamic hydrogels

FVIOs

generating heat and maintaining rheological integrity; promote DOX to enter the nuclei of cancer cells

breast cancer

MHT-Chemotherapy

[100]

DOX-loaded magnetic alginate-chitosan microspheres

SPIONs

realizing magnetic hyperthermia agents and drug release triggers

breast cancer

MHT-Chemotherapy

[101]

Gallic acid-ferrous

Fe3+

realizing NIR absorbing Fenton catalyst

breast cancer

CDT-starvation therapy

[86]

Hyaluronic acid-gallic acid

Fe3+

absorbing NIR light energy to vibrating heat energy

skin and breast cancers

PTT

[104]