Table 9 Toxicity data, 4 h exposure, without metabolic activation
From: ISO 10993 biological evaluation of novel hemostatic powder – 4SEAL®
Sample | Number of cells seeded (*10^5) | Number of cells 24 h after treatment (*10^5) | Number of cells 48 h after treatment (*10^5) | Total suspension growth | Relative Suspension Growth (RSG) [%] | Plating Efficiency [%] | Relative Plating Efficiency (RPE) [%] | Relative Total Growth (RTG) [%] |
|---|---|---|---|---|---|---|---|---|
NC1 | 3 | 11.02 | 9.03 | 16.59 | 100.00 | 93.59 | 100.00 | 100.00 |
NC2 | 3 | 10.56 | 9.11 | 16.03 | ||||
PC | 3 | 8.62 | 7.67 | 11.02 | 67.56 | 65.80 | 70.31 | 47.50 |
4SEAL® 1 | 3 | 10.38 | 8.97 | 15.52 | 95.15 | 92.08 | 98.39 | 93.62 |
4SEAL® 2 | 3 | 10.62 | 9.02 | 15.97 | 97.89 | 87.96 | 93.99 | 92.01 |