Table 7 AMES assay results
From: ISO 10993 biological evaluation of novel hemostatic powder – 4SEAL®
Strain | without S9 | with S9 | ||||
|---|---|---|---|---|---|---|
Baseline | Fold increase over baseline | Binomial B-value | Baseline | Fold increase over baseline | Binomial B-value | |
TA98 | 1.00 | 1.33 | 0.82 | 3.75 | 0.18 | 0.12 |
TA100 | 9.00 | 0.81 | 0.17 | 14.61 | 0.64 | 0.19 |
TA1535 | 3.91 | 0.68 | 0.32 | 1.00 | 17.00 | 1.00 |
TA1537 | 1.82 | 0.55 | 0.86 | 2.00 | 0.50 | 0.65 |
E.coli uvrA [pKM101] | 9.39 | 0.46 | 0.08 | 10.0 | 0.40 | 0.00 |