Table 6 Average size of alginate microparticles prepared using droplet-based microfluidics with different gelation methods
Average size of microparticles | Gelation method | Reference |
|---|---|---|
1–50 μm 10–300 nm | Internal gelation with water-soluble cross-linkers mixed with Na-alginate before droplet generation | Rondeau and Cooper-White 2008a [39] |
50–300 μm | Internal gelation with water-soluble cross-linkers mixed with Na-alginate after droplet generation | Xu et al. 2008 [54] |
20–50 μm | Liu et al. 2006 [28] | |
22–42 μm | Trivedi et al. 2009 [48] | |
60–100 μm | Internal gelation with water-insoluble cross-linkers mixed with Na-alginate after droplet generation | Zhang et al. 2007 [61] |
26 μm | Akbari and Pirbodaghi 2014 [3] | |
50–100 μm | Yu et al. 2019 [56] | |
10–50 μm | Internal gelation with slightly water-soluble cross-linkers mixed with Na-alginate after droplet generation | Utech et al. 2015 [49] |
50–70 μm | External gelation with on-chip introduction of cross-linkers | Zhang et al. 2007 [61] |
147–176 μm | Liu et al. 2019 [29] | |
5–10 μm | Pittermannová et al. 2016a [34] | |
6–10 μm | Sugaya et al. 2011a [44] | |
100–200 μm | External gelation with off-chip introduction of cross-linkers | Hu et al. 2012 [20] |
7–40 μm | Zhang et al. 2020a [59] |