Fig. 5
From: ι-Carrageenan nanocomposites for enhanced stability and oral bioavailability of curcumin
In vitro permeability and absorption mechanism of Cur@CRN. (A) Schematic process of the permeability test via the transwell system. (B) Permeabilities of various compounds across the MDCK and Caco-2 cell monolayers (Paap values are presented in Supplementary Table S2, n = 3). (C) Competitive inhibition test by co-incubating free CRN with various nanocomposites (n = 3). (D) Confocal images of colocalization between SLC26A2 and Tw80-FITC, HPC-FITC, and CRN-FITC in various cells (5 μg/mL, Cur equivalent) (starting from the top panel, Caco-2; positive cells, L929 and MDCK; negative cells)