Fig. 3

The swelling ratios of core-shell beads with various in chitosan/xanthan-gum (C/X) formulation in pH = 2 buffer (n ≥ 4). The times for immersion were 1, 2, 4, 6, 8, 12 and 24 h. The results were pooled in accordance with formulation (a) and with immersion period (b). In (a), the significance from ANOVA test from 1 h to 6 h with fixed formulation was marked by * (p < 0.05), ** (p < 0.01) and *** (p < 0.005) for indicated groups. In (b), the significance from ANOVA test for C/X ratio with fixed immersion time was marked by *** (p < 0.005)