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Fig. 4 | Biomaterials Research

Fig. 4

From: Comparison of demineralized bone matrix and hydroxyapatite as carriers of Escherichia coli recombinant human BMP-2

Fig. 4

Histology sections. a Histology sections in the 4th week. ErhBMP-2 2.5 μg + DBM showed significantly more solid bone regeneration, less adipose tissue formation than ErhBMP-2 25 μg + HA and ErhBMP-2 2.5 μg + HA groups. In both groups with HA as carrier, cyst-like bone and abundant adipose tissue formed in the defect. b Histology sections in the 8th week. ErhBMP-2 2.5 μg + DBM group still had the most bone regeneration. ErhBMP-2 25 μg + HA had more adipose tissue formed inside the defect and more hollow structure compared with 4th week. The bone in ErhBMP-2 2.5 μg + HA had less cyst-like bone and adipose tissue than ErhBMP-2 25 μg + HA group had. The DBM group had less bone compared with its 4th week. The green triangles indicated the HAP granules and the cyan diamonds indicated the newly formed bone. The data in DBM + ErhBMP-2 group was reported in a previous article [20]

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Biomaterials Research

ISSN: 2055-7124

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