Fig. 4
Quantification of Ca2+ in cell culture medium by ICP-MS over a period of 21 days of cell culture in basic or differentiation medium. a For uncoated BiominCol membranes, no major differences between the basic and differentiation medium were observed, indicating that resorption by osteoclasts was limited or non-existent. b For CoCaP-coated BiominCol membranes, a significantly higher Ca2+ concentration was seen for the differentiation condition on day 2 (p = 0.37), day 9 (p < 0.001) and day 16 (p = 0.016)