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Table 2 The advantages and disadvantages of three methods of providing ES

From: Electrical stimulation as a novel tool for regulating cell behavior in tissue engineering

Methods

Advantages

Disadvantages

Direct coupling [59]

Easy operation

Insufficient biocompatibility of the electrode, contact with the medium lead to temperature rise, pH changes, and the generation of harmful byproducts

Capacitive coupling [64]

More biologically safe

High voltage between the electrodes, longer treatment time

Inductive coupling [62]

Mimic the natural potential transfer in the human body, does not directly touch cells

Tumorigenesis in unexpected area, taking time and resource consumption