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Table 2 The advantages and disadvantages of three methods of providing ES

From: Electrical stimulation as a novel tool for regulating cell behavior in tissue engineering

MethodsAdvantagesDisadvantages
Direct coupling [59]Easy operationInsufficient biocompatibility of the electrode, contact with the medium lead to temperature rise, pH changes, and the generation of harmful byproducts
Capacitive coupling [64]More biologically safeHigh voltage between the electrodes, longer treatment time
Inductive coupling [62]Mimic the natural potential transfer in the human body, does not directly touch cellsTumorigenesis in unexpected area, taking time and resource consumption