Fig. 11
From: Therapeutic efficacy of nanoparticles and routes of administration
Pulmonary drug delivery via inhalation. The concept of nanoparticle incorporated drugs for pulmonary delivery is, when it is inhaled it will pass through oropharynx and deposited in alveoli of lungs with the help of suitable inhalation devices. The pulmonary device containing nanoparticle coated drugs, when inhaled will pass through oropharynx and deposited in the alveoli of lungs. Subsequently, the nanoparticle coated drug aids in sustained release of drugs from the lungs and thus improved distribution in systemic circulation. It offers high surface area with rapid absorption vascularization and circumvention of the first pass effect