Fig. 2

pH and serum stability of hIgG1-Fc-9Arg/pAcGFP-N1 complex. a Stability of the hIgG1-Fc-9Arg protein at various pH conditions (pH 1.5, 5.0, 6.0 and 7.4). b Stability of pDNA at 50/1 ratio of hIgG1-Fc-9Arg/pDNA complexes in the stomach environment (pH 2.0). c Serum stability of the complex. Naked pDNA and various ratios of hIgG1-Fc-9Arg/pDNA complexes were treated with 10% fetal bovine serum (FBS) at various time intervals (0, 0.5, 2, 4, 7, 10, 12, 24 h). Complexes were released by adding 1% SDS to determine the damage of pDNA. Representative images from at least three results