Fig. 2
From: Lipid-based surface engineering of PLGA nanoparticles for drug and gene delivery applications
Advantage and application of different lipids-surface engineering on PLGA nanoparticles. The bare PLGA nanoparticles have major drawbacks such as hydrophobic surface, rapid phagocytic clearance and initial burst release. Cell membrane derived lipid vesicles or synthetic lipids based surface engineering on PLGA nanoparticles prevent the fore told drawbacks and improve the clinical performance