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Fig. 5 | Biomaterials Research

Fig. 5

From: Guided bone regeneration using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-cross-linked type-I collagen membrane with biphasic calcium phosphate at rabbit calvarial defects

Fig. 5

Higher magnification view of the defect sites at 8 weeks, Trichrome staining. (a) Histologic view of CM group showing islets of new bone (NB) integrated within the CM at the middle of the defect. Depression of the collapsed CM and elevation of the dura mater (DM) resulting in subsequent elimination of defect space. Nevertheless, new bone (NB) formation occurred integrated within the CM. (b) Histologic view of collagen membrane (CM) in the B-CM group showing new bone (NB) integrated to the network of collagen membrane. CM is closely adapted to the native bone (OB) at the defect perimeter. Effective space provision is provided by the bone graft (BG) particles. Vascularization of the membrane can be seen throughout the membrane (arrows)

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Biomaterials Research

ISSN: 2055-7124

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