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Fig. 4 | Biomaterials Research

Fig. 4

From: Liposomes targeting the cancer cell-exposed receptor, claudin-4, for pancreatic cancer chemotherapy

Fig. 4

In vivo therapeutic efficacy of Dox-loaded liposomes in a KPC960 xenograft model. A In vivo biodistribution of Cy5.5-labeled liposomes. B Changes in tumor volume with a 15-day treatment. C Average weight of excised tumors after a 15-day treatment. D Apoptotic cell death after a 15-day treatment, assessed by TUNEL assay. E Ex vivo findings showing fluorescence images of tumors excised from mice treated with Cy5.5-labeled liposomes after a 15-day treatment. F Quantification of ex vivo results (n = 4). (*P < 0.05, **P < 0.01)

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