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Fig. 5 | Biomaterials Research

Fig. 5

From: Effervescent cannabidiol solid dispersion-doped dissolving microneedles for boosted melanoma therapy via the “TRPV1-NFATc1-ATF3” pathway and tumor microenvironment engineering

Fig. 5

Influence on the tumoral immune cells. (A) Representative flow cytometric analysis and quantitative analysis of M1-like macrophages (CD86+) and M2-like macrophages (CD206+) gated on CD45+CD11b+F4/80+ cells after different treatments. Data are represented as mean ± SD, n = 5. **P < 0.01. ***P < 0.001. (B) Representative flow cytometric analysis and quantitative analysis of helper T cells (CD4+) and cytotoxic T cells (CD8+) gated on CD45+CD3+ cells after different treatments. Data are represented as mean ± SD, n = 5. *P < 0.05. **P < 0.01. (C) Representative flow cytometric analysis and quantitative analysis of dendritic cell (MHC II+) gated on CD45+CD11b− cells after different treatments. Data are represented as mean ± SD, n = 5. **P < 0.01

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Biomaterials Research

ISSN: 2055-7124

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