Fig. 10
From: Molecularly imprinted polymers (MIPs): emerging biomaterials for cancer theragnostic applications
A Synthesis process of capsule-like molecularly imprinted polymers (MIPs) nanoparticles (NPs) as drug carriers with chemo-photothermal therapeutic effects. Photothermal heating curves of the MIP water solution (B) with various concentrations and (C) various power density under 808 nm laser irradiation. D Cell viabilities of 16HBE cells incubated with doxorubicin (DOX)@MIP (MD), DOX@NIP (ND), zeoliticimidazolate framework-8 (ZIF-8)@DOX (ZD), and DOX at pH = 7.4 (MD, ND, ZD, DOX), E pH = 5.0 (MD-A, ND-A, ZD-A), and with near-infrared (NIR) laser irradiation (MD-NIR, MD-A-NIR) (808 nm, 1.5 W/cm2, 5 min). F Cell viabilities of A549 cells incubated with MD, ND, ZD, DOX at pH = 7.4 (MD, ND, ZD, DOX), G pH = 5.0 (MD-A, ND-A, ZD-A), and with NIR laser irradiation (MD-NIR, MD-A-NIR) (808 nm, 1.5 W/cm.2, 5 min). The cells were pretreated with acidic PBS (pH = 5.0, denoted as X-A). X represents MD, ND or ZD. A, B, C, D, E, F, G Reproduced with permission from [153], published by Elsevier 2021