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Fig. 7 | Biomaterials Research

Fig. 7

From: Self-assembled peptide-substance P hydrogels alleviate inflammation and ameliorate the cartilage regeneration in knee osteoarthritis

Fig. 7

(A) Apoptotic cells (green) in the knee joint cartilage were detected 6 and 12 weeks after spontaneous induction of OA by TUNEL staining in the articular cartilage regions. The ratio of TUNEL-positive nuclei to total nuclei was quantified in each group (expressed as %, n = 4 in each group). Scale bars: 25 μm (*, p < 0.05). (B) MMP-9 and type II collagen were detected by immunofluorescence staining. (DAPI: blue, MMP-9: green, type II collagen: red) Scale bars: 100 μm. (C) MSC recruitment of SAP-SP conjugates was investigated. The representative images of articular cartilage defect site from each group after CD29 (green) and CD90 (red) staining. Scale bars: 100 μm

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Biomaterials Research

ISSN: 2055-7124

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