Fig. 4
From: CRISPR/Cas9 assisted stem cell therapy in Parkinson's disease
Applications of CRISPR Cas9 tool in Parkinson's Disease. A. In-vitro application of CRISPR/Cas9 tool. Plasmids, Cas9 mRNA, SgRNA, or whole Ribonucleoprotein can be delivered into the biological systems using various methods. In-vitro applications in PD include the identification of pathogenic genes, model development, and the development of therapeutic strategies. B. In vivo applications of the CRISPR/Cas9 tool includes PD model development and screening of therapeutic strategies