Table 8 Other polymer dressings
Dressing Biomaterials | Polymer composite | Loaded substances | Animal models | Cell strains | Properties | Properties and advantages | Disadvantages | Ref. |
|---|---|---|---|---|---|---|---|---|
Films | PLCL+hyaluronic | ZnO nanoparticles + oregano essential oil (OEO) | Male Sprague Dawley rats (weighing 200 ~300 g) | NIH-3T3 cells | Exchange gases; Absorbing wound exudates | Translucent; Breathable; Autolytic cleansing | Poor water absorption | [268] |
PLGA+curcumin NFMs | Heparin+ curcumin | Male fifteen-week-old SD rats (weighing 200~250 g) | Human skin fibroblast cell (HS68) | Promotes cell proliferation and migration | [269] | |||
Cellulose acetate+ zein | Sesamol | Male eight-week-old C57BL/6 J clean-grade mice | NA | Antioxidant; Anti-inflammatory; Release controllable | [270] | |||
Sponges | PVA+chitosan | Pinus densiflora-iron oxide nanoparticles | NA | HEK-293 cells | Antibacterial; Hemostasis; Good permeability | High porosity and surface area; Moisture maintenance in wound area | Poor mechanical strength; Insufficient antibacterial properties | [271] |
Chitosan | Quaternary ammonium chitosan nanoparticles | Male adult Kunming mice (weighting 35 ± 3 g) | L929 cells | Bacteriostatic; Hydration; Pro-angiogenesis | [272] | |||
Chitosan+silk | Curcuma zedoaria +PRP-Exos | Female Sprague-Dawley (SD) rats (weighing 280 ~300 g) | NA | Easy to produce; Pro-angiogenesis; Anti-inflammatory | [273] | |||
Hydrocolloid | Sodium Alginate | Centella asiatica (CA) | Male 6–7 weeks old Sprague-Dawley rats (weighting 250–280 g) | NA | High mechanical strength; Antibacterial | Exudate absorption; Adhesion; Autolytic cleansing | Poor adhesion; non-breathable | [274] |
Sodium Alginate-pectin | Moringa oleifera (MOL) | Male 6 to 8-week-old Sprague Dawley rats (weighing 150 ~200 g) | NA | Anti-inflammatory; Antimicrobial; Biocompatibility | [275] | |||
Sodium Alginate | Vicenin-2 | Male 7–8 weeks old Sprague Dawley rats (weighing 150 ~250 g) | NA | Antioxidant; Anti-inflammatory;Pro-proliferation and migration of cells | [276] | |||
Foams | Curdlan–chitosan | Ag nanoparticles | Female 5-month-old K.S.Cg Dock7 +/+Lepr /J mice ( weighting 30~40 g;) | NA | Hydration; Antimicrobial | Moisture maintenance in wound area; Shape memorability | Wound impregnation; Frequent replacement | [277] |
Polyurethanes | rhEGF | Male 6-7 weeks old SD rats | HaCaT human keratinocytes+CCD986-sk human fibroblast | Promote the proliferation of fibroblasts; Promote the formation of extracellular matrix | [278] | |||
HPMC/chitosan / sodium alginate +Polyurethane | Asiaticoside | Domestic farm pigs with an average (weighting 20~25 kg) and three rabbits | Human fibroblasts | Antibacterial; Hemostasis; Promoting epithelialization | [279] | |||
Microspheres | Gelatin | rADSCs | 8-weeks-old Sprague-Dawley rats (weighting 250~300 g) | HUVECs | Promote M2 macrophage polarization; angiogenesis; adhesion and proliferation | Biodegradability; Biocompatibility; Sustained-release drugs | Cumbersome preparation; Unstable embedding rate; Uncontrollable degradation rate | [280] |
PVA+chitosan grafted with phenylboric acid +celecoxib | Insulin+gelatin microspheres | Male 14-weeks old SD rats | L929 cells | Promote cell proliferation and migration | [146] | |||
Gelatin microspheres | Curcumin | Female BALB/c mice (weighting 18~20 g) | BJ cells and HaCat cells | Antioxidant; Anti-inflammatory; Promote cell proliferation | [281] |