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Fig. 8 | Biomaterials Research

Fig. 8

From: Advanced polymer hydrogels that promote diabetic ulcer healing: mechanisms, classifications, and medical applications

Fig. 8

Injectable bioglass/sodium alginate (BG/SA) hydrogel loaded with MMP9-siNPs. (a) Schematic diagram of siNP-BG/SA hydrogel preparation. (b) Gross observation images and wound closure rates of wounds in the control, rsiNP, BG/SA, and rsiNP-BG/SA groups on days 0, 7, and 12. (c) Low magnification observation of MMP-9 IF staining of wound tissues. (d) High magnification observation of MMP-9 IF staining of wound tissues. (e) Quantitative statistics of MMP-9-positive areas in wound tissues. Reproduced from [185] with permission from Elsevier Copyright 2022

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