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Fig. 6 | Biomaterials Research

Fig. 6

From: A multi-targeting bionanomatrix coating to reduce capsular contracture development on silicone implants

Fig. 6

A qRT-PCR analysis of TGF-β1, COLL Iα, COLL IαII, and CTGF expressions from the capsule tissues. *p < 0.05 and **p < 0.01 between two groups. B Western blot analysis of TGF-β1, α-SMA, and COLL Iα expressions from the capsule tissues. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001 between two groups. C IHC analysis of p-SMAD2 and 3 from the capsule tissues. Scale bar: 100 μm. **p < 0.01 and ****p < 0.0001 between two groups. D Western blot analysis of p-SMAD2/3 expressions from the capsule tissues. **p < 0.01 between two groups. Sham: no implantation (negative control), Cont: Uncoated silicone, NO-30: 30 layers of bionanomatrix coated silicone, and NO-60: 60 layers of bionanomatrix coated silicone

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Biomaterials Research

ISSN: 2055-7124

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